继发性甲状旁腺功能亢进症57例手术治疗临床分析

发布时间：2018-04-26 06:34

  本文选题：甲状旁腺切除术 + 尿毒症　； 参考：《重庆医学》2017年18期

【摘要】：目的探讨甲状旁腺全部切除加自体移植术(PTX+AT)治疗尿毒症维持性透析患者继发性甲状旁腺功能亢进症(SHPT)的临床疗效及术后的补钙治疗措施。方法对2015年3-8月于南京医科大学第一附属医院/江苏省人民医院肾内科接受PTX+AT治疗的57例SHPT患者临床资料进行回顾性分析,观察手术前后血清全段甲状旁腺激素(iPTH)、血钙及临床症状等变化。结果术后不同时间[即刻、20min、第2天、第4天血iPTH分别为(288.57±194.71)、(185.00±99.28)、(83.83±58.26)、(17.91±15.60)pg/mL],较术前iPTH[(2 395.80±829.04)pg/mL]明显下降(P0.01);术后4、8、24、72h血钙分别为(2.34±0.32)、(2.16±0.37)、(2.16±0.27)、(2.25±0.25)mmol/L,较术前血钙(2.61±0.25)mmol/L明显下降(P0.05);骨痛、皮肤瘙痒等临床症状明显改善。结论 PTX+AT可以有效地治疗尿毒症SHPT,术后及时补钙可减少低钙血症的发生。
[Abstract]:Objective to investigate the clinical effect of total parathyroidectomy and autograft PTX ATT in the treatment of secondary hyperparathyroidism in uremic maintenance dialysis patients. Methods the clinical data of 57 patients with PTX treated with PTX AT in Department of Nephrology, first affiliated Hospital of Nanjing Medical University / people's Hospital of Jiangsu Province from March to August 2015 were retrospectively analyzed. The changes of serum total parathyroid hormone iPTHG, serum calcium and clinical symptoms were observed before and after operation. 缁撴灉鏈�鍚庝笉鍚屾椂闂碵鍗冲埢,20min,绗，

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