退行性腰椎管狭窄症与腰椎矢状位曲度异常相关性研究

发布时间：2018-04-26 08:01

本文选题：退行性腰椎管狭窄症 + 腰椎曲度　；参考：《郑州大学》2017年硕士论文

【摘要】：目的研究退行性腰椎管狭窄症腰椎曲度异常与狭窄程度的相关性,以探讨腰椎管狭窄病变的发展规律,为了解病变程度、制定治疗方案、判断预后以及评价疗效提供理论依据。方法回顾性分析2014年1月至2016年12月于郑州大学第一附属医院骨科收治的腰椎管狭窄患者资料,根据纳入标准和排除标准,选取患者59例作为观察组(A组),并选取55例健康体检者作为正常对照组(B组)。两组根据性别各分为男女亚组。所有对象均接受腰椎MRI检查,在MRI矢状像上以腰椎前凸中心法(CLL)测量腰椎曲度。并对A组在MRI轴位像上测量硬膜囊面积(DAC)、骨性椎管面积(BAC)、硬膜囊面积/骨性椎管面积(DAC/BAC)。AB两组CLL角比较采用独立样本t检验。A组中CLL角与DAC、BAC、DAC/BAC关系应用Pearson相关性分析。P0.05为差异有统计学意义?结果1.(1)A组男女CLL平均角度分别为9.26±3.18;10.56±3.21。B组男女CLL平均角度分别为12.59±1.84;22.32±3.19。?A组与B组男女CLL角度相比均具有差异有统计学意义(男、女t值分别为3.042,5.784;p值分别为0.004,0.000)。2.(1)A组男女DAC平均面积分别为85.34±20.02,78.96±11.71;男女BAC平均面积分别为220.42±18.76,220.90±10.30;男女DAC/BAC平均比值分别为0.387±0.084,0.357±0.048。(2)A组男女CLL角与DAC均具有显著相关性(男女r值分别为0.788,0.841;p值均为0.000)。A组男女CLL角与DAC/BAC均具有显著相关性(男女r值分别为0.754,0.850;p值均为0.000)。A组男女CLL角与BAC均无显著相关性(男女r值分别为0.319,0.245;p值分别为0.075;0.218)。结论1.退行性腰椎管狭窄症患者较健康人腰椎曲度变直。2.腰椎管狭窄程度与腰椎曲度异常有显著正相关性。
[Abstract]:Objective to study the relationship between the degree of lumbar curvature and the degree of degenerative lumbar spinal stenosis in order to explore the development rule of lumbar spinal stenosis, and to provide theoretical basis for understanding the degree of disease, formulating treatment plan, judging prognosis and evaluating curative effect. Methods from January 2014 to December 2016, the data of patients with lumbar spinal stenosis treated in the Department of Orthopaedics of the first affiliated Hospital of Zhengzhou University were retrospectively analyzed. 59 patients were selected as observation group A and 55 healthy persons as normal control group. The two groups were divided into male and female subgroups according to gender. All subjects underwent lumbar MRI examination and lumbar curvature was measured on MRI sagittal images. In group A, the area of dural sac, the area of bony spinal canal and the area of dural sac / bony spinal canal were measured on the axial images of MRI. The CLL angle of group A was compared with that of group A by using independent sample t test. Pearson correlation analysis was used to analyze the relationship between CLL angle and DACBACDAC- BAC in group A. P0.05 for the difference was statistically significant? Results 1. The average angle of CLL in group A was 9.26 卤3.18 卤10.56 卤3.21.B, respectively. The mean angle of CLL in group A was 12.59 卤1.84 卤3.19.0.32 卤3.19.A, respectively. There was significant difference in CLL angle between group A and group B (male, male). The mean area of DAC in group A was 85.34 卤20.02 卤78.96 卤11.71, the mean area of BAC in men and women was 220.42 卤18.76220.90 卤10.30, and the average ratio of DAC/BAC was 0.387 卤0.0840.357 卤0.048.2P in group A (r = 0.7880.841p for males and females, respectively). There was significant correlation between CLL angle and DAC/BAC in group A (r = 0.7540.50p). There was no significant correlation between CLL angle and BAC in group A (r = 0.3190.245p = 0.0750.218p, respectively). Conclusion 1. The lumbar curvature of degenerative lumbar spinal stenosis patients was straightened. 2. There was a significant positive correlation between lumbar spinal stenosis and abnormal lumbar curvature.
【学位授予单位】：郑州大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R681.5

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