局部应用氨甲环酸结合夹闭引流管对全髋关节置换术后失血量影响的研究

发布时间：2018-04-26 17:17

本文选题：氨甲环酸 + 全髋关节置换术　；参考：《山东中医药大学》2017年硕士论文

【摘要】：目的:探讨髋关节腔内注射氨甲环酸结合夹闭引流管对减少全髋关节置换术失血的有效性和安全性。方法:回顾性研究山东中医药大学附属医院2015年3月至2016年12月期间符合要求的单侧全髋关节置换术的患者120例,其中试验组60例,局部应用氨甲环酸;对照组60例,不应用氨甲环酸。两组均在关节腔内放置引流管一根并采用自体血回输器。对两组患者术后引流量、失血量、输血量、Harris髋关节评分及相关并发症等,进行统计学分析。结果:局部应用氨甲环酸组与对照组比较,在性别、年龄、体重指数等一般资料方面无明显差异(P0.05)。局部应用氨甲环酸组比对照组在术后引流量、术后3d的显性失血量、总失血量、输血量等方面均有所减少,差异具有统计学意义(P0.05),在隐性失血量方面无统计学差异(P0.05)。在术后并发症方面,两组患者在DVT、下肢淋巴水肿、皮下瘀斑、肺部感染等方面比较,其差异均无统计学意义(P0.05)。在术后3月髋关节Harris评分方面,两组无显著差异(P0.05),且评分均有所提高。结论:在全髋关节置换术中,关节腔内注射氨甲环酸结合短期夹闭流管能够减少术后引流量、总失血量、异体血使用量,且不增加并发症的发生率,不影响术后髋关节功能的恢复。
[Abstract]:Objective: to investigate the efficacy and safety of intra-articular injection of aminocyclylic acid combined with clipping drainage tube in reducing blood loss in total hip arthroplasty (THR). Methods: a retrospective study of 120 patients with unilateral total hip replacement (THR) from March 2015 to December 2016 in the affiliated Hospital of Shandong University of traditional Chinese Medicine, including 60 cases in the experimental group, 60 cases in the experimental group and 60 cases in the control group, No carbamate is used. One drainage tube was placed in the articular cavity and autologous blood transfusion device was used in both groups. The postoperative drainage, blood loss, Harris hip score and related complications were analyzed statistically. Results: there was no significant difference in sex, age and body mass index between the two groups. The amount of dominant blood loss, the total amount of blood loss and the amount of blood transfusion in the local application group were lower than those in the control group. The difference was statistically significant (P 0.05), but there was no significant difference in the hidden blood loss (P 0.05). In terms of postoperative complications, there was no significant difference in DVT, lower extremity lymphedema, subcutaneous ecchymosis and pulmonary infection between the two groups. There was no significant difference in Harris score of hip joint between the two groups at 3 months after operation (P 0.05), and the score was improved. Conclusion: in total hip arthroplasty, intraarticular injection of carbamoic acid combined with short-term clipping can reduce postoperative drainage, total blood loss, allogeneic blood consumption, and do not increase the incidence of complications. The recovery of hip function was not affected after operation.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R687.4

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