脂肪溶解液用于乳腺癌腋窝淋巴结解剖

发布时间：2018-04-27 20:10

本文选题：乳腺癌 + 腋窝淋巴结　；参考：《暨南大学学报(自然科学与医学版)》2017年05期

【摘要】：目的:探讨脂肪溶解液预处理在解剖乳腺癌腋窝淋巴组织标本中的应用价值并分析影响解剖结果的因素.方法:施行乳腺癌改良根治术患者156例,实验组80例,予脂肪溶解液浸泡15~20 min后进行解剖,对照组76例按照传统方法解剖.比较两组在解剖淋巴结的数目及解剖时间等方面的差异,进一步分析年龄、肥胖及淋巴结分期等因素对解剖结果的影响.结果:实验组解剖淋巴结的数目(23.69)明显多于对照组(18.56),解剖时间(19.83 min)明显少于对照组(24.15 min).分层分析发现年龄和淋巴结的转移数目对两组间淋巴结解剖结果的差异无影响;肥胖对解剖结果的差异影响较大,特别是肥胖患者两组间检出淋巴结数目的差值(7.12)显著高于非肥胖患者(3.67).结论:脂肪溶解液处理腋窝淋巴结可增加腋窝淋巴结解剖的数目,降低解剖难度,尤其适用于肥胖患者,此方法的解剖效果与年龄及淋巴结分期无关.
[Abstract]:Objective: to investigate the application value of adipose solution pretreatment in dissecting axillary lymphoid tissue of breast cancer and analyze the factors influencing the anatomical results. Methods: 156 patients with breast cancer underwent modified radical mastectomy and 80 patients in experimental group were dissected after 15 ~ 20 min immersion in adipose solution, while 76 cases in control group were dissected according to traditional methods. The number and duration of anatomic lymph nodes were compared between the two groups, and the influence of age, obesity and lymph node staging on the anatomic results was analyzed. Results: the number of dissected lymph nodes in the experimental group was 23.69) and the anatomic time was 19.83 min, which was significantly lower than that in the control group (24.15 min). Stratified analysis showed that age and the number of lymph node metastasis had no effect on the difference of anatomical results of lymph nodes between the two groups, but obesity had a great influence on the differences of anatomical results. In particular, the difference in the number of lymph nodes detected between the two groups was significantly higher than that in non-obese patients (P < 7.12). Conclusion: the treatment of axillary lymph nodes with adipose solution can increase the number of axillary lymph nodes and reduce the anatomic difficulty, especially for obese patients. The anatomical effect of this method is not related to age and lymph node staging.
【作者单位】：暨南大学附属第一医院乳腺外科;广西壮族自治区南溪山医院乳腺甲状腺外科;
【基金】：广东省医学科学技术研究基金项目(A2015319)
【分类号】：R737.9

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