全麻诱导期经静脉输液管缓慢滴注和快速输注芬太尼对该药诱发呛咳的影响（英文）

发布时间：2018-04-28 22:21

本文选题：全麻 + 芬太尼诱发呛咳　；参考：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2017年11期

【摘要】：目的:探讨全麻诱导期经静脉输液管(墨菲氏管)给药能否减轻芬太尼诱发的呛咳。创新点:寻找一个简单易行、安全可靠的方法减轻全麻诱导期芬太尼诱发的呛咳。与既往芬成尼和呛咳相关的研究相比,本研究试验组操作不仅简便、快速,而且无需额外使用其它药物或设备,不增加人力成本或病人经济负担。方法:择期行全身麻醉手术1138例,所有患者均采用咪达唑仑-芬太尼-丙泊酚-顺式阿曲库铵-气管插管麻醉,随机分为静脉输液管缓慢滴注组(S组,573例)与经三通快速输注组(C组,565例),记录麻醉诱导期两组患者呛咳发生率及严重程度和其它不良反应发生情况。结论:静脉输液管缓慢滴注组呛咳发生率及严重程度较快速输注组明显降低,其它不良反应发生率比较差异无统计学意义。全麻诱导期经静脉输液管缓慢滴注芬太尼可明显降低该药所致呛咳的发生率,且该法简单易行、安全可靠,值得推广。
[Abstract]:Aim: to investigate whether the intravenous infusion tube (Murphy's tube) can alleviate the cough induced by fentanyl during induction of general anesthesia. Innovation: find a simple, safe and reliable way to relieve cough induced by fentanyl during general anesthesia. Compared with previous studies related to fenchonil and cough, the operation of this study group is not only simple and rapid, but also does not require the additional use of other drugs or equipment, and does not increase the cost of labor or economic burden of patients. Methods: 1138 patients undergoing general anesthesia were treated with midazolam fentanyl propofol cis atracurium tracheal intubation anesthesia. The patients were randomly divided into two groups: group S (573 cases) and group C (565 cases). The incidence and severity of cough and other adverse reactions were recorded in the two groups during the induction period of anesthesia. Conclusion: the incidence and severity of cough in the slow infusion group were significantly lower than those in the fast infusion group, but there was no significant difference in the incidence of other adverse reactions. The slow infusion of fentanyl through intravenous infusion tube during the induction of general anesthesia can significantly reduce the incidence of cough caused by the drug, and the method is simple, safe and reliable, and worth popularizing.
【作者单位】： Institute
【分类号】：R614

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