不同椎间植骨材料治疗颈脊髓压迫症的临床疗效分析

发布时间：2018-04-29 20:47

本文选题：同种异体骨 + 聚醚醚酮　；参考：《安徽医科大学》2017年硕士论文

【摘要】：目的:研究不同椎间植骨材料治疗脊髓型颈椎病和椎间盘突出症的临床疗效分析。方法:回顾分析安徽医科大学第一附属医院2011年9月至2013年8月颈椎间盘突出症患者共63名,按照椎间植骨材料的不同将其分成同种异体骨环组(A组)男/女为12/11,Cage组(B组)男/女为11/7和自体髂骨组(C组)男/女为13/9,统计各样本的年龄,性别,住院号,手术时间,出血量,并发症,融合节段椎体前后高度差值(HAB/HPB),手术节段Cobb角和神经功能改善(mJOA评分)。结果:1.所有患者均完成术后12-18个月的随访,三组患者术后6个月融合率分别为23.2%(A组),22.7%(B组),25.3%(C组),三组患者术后1年融合率分别为86.3%(A组),81.5%(B组),88.3%(C组)。2.A组与C组,B组与C组组间手术时间,术中出血量,HAB/HPB,Cobb角差异有统计学意义(P0.05),A组与B组组间手术时间,术中出血量,HAB/HPB,Cobb角无明显差异(P0.05)。A组有1例出现骨环断裂,B组有1例出现Cage移位,C组有4例出现髂骨区疼痛。结论:1.术后前3个月,自体髂骨的HAB/HPB差值和Cobb角改变最明显,其次是同种异体骨,Cage变化最小。2.采用同种异体骨,Cage和自体髂骨作为椎间植骨材料治疗颈脊髓压迫的融合率相当,同种异体骨环和Cage可作为理想的椎间植骨材料。
[Abstract]:Objective: to study the clinical effect of different intervertebral bone graft materials in the treatment of cervical Spondylotic myelopathy and disc herniation. Methods: a total of 63 patients with cervical disc herniation from September 2011 to August 2013 in the first affiliated Hospital of Anhui Medical University were retrospectively analyzed. According to the different bone graft materials, the bone grafts were divided into two groups: group A (male / female: 12 / 11 Cage group, group B) (male / female = 11 / 7) and autogenous iliac bone group (group C) (13 / 9). The age, sex, hospitalization number and operation time of each sample were counted. Blood loss, complications, anterior and posterior height difference of fusion segment vertebrae, Cobb angle of surgical segment and improvement of nerve function were evaluated. The result is 1: 1. All the patients were followed-up 12-18 months after operation. The fusion rates of the three groups were 23.2and 22.7B, respectively. One year after operation, the fusion rates of the three groups were 86.3% and 81.5%, respectively, and the time of operation between group A and group C was higher than that between group B and group C, and the time of operation between group B and group C was higher than that of group C, respectively. There was significant difference in blood loss during operation between group A (P 0.05) and group B (P 0.05). There was no significant difference in blood loss during operation between group A and group B. there was no significant difference in blood loss during operation between group A and group B. There was no significant difference in the volume of blood loss between group A and group B (P 0.05). There was 1 case of bone ring rupture in group B and 1 case in group C had Cage shift. 4 cases had pain in iliac region. Conclusion 1. In the first 3 months after operation, the difference of HAB/HPB and Cobb angle of autogenous iliac bone was the most obvious, followed by the least change of Cage of allograft. The fusion rate of allograft Cage and autogenous iliac bone graft in the treatment of cervical spinal cord compression was similar, and allograft bone ring and Cage could be used as ideal intervertebral bone graft materials.
【学位授予单位】：安徽医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R687.3

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