硝酸甘油对深低温停循环心肺转流降温和复温的影响

发布时间：2018-05-01 09:09

本文选题：硝酸甘油 + 心肺转流　；参考：《临床麻醉学杂志》2017年06期

【摘要】：目的探讨硝酸甘油对深低温停循环心肺转流(deep hypothermic circulatory arrest cardiopulmonary bypass,DHCAC)降温和复温的影响。方法选择行DHCAC下全主动脉弓置换手术患者46例,男38例,女8例,年龄26~74岁,ASAⅣ或Ⅴ级,随机分为研究组(n=24)和对照组(n=22)。两组均采用相同的变温方法。研究组在降温和复温期间持续静脉泵入硝酸甘油,对照组则泵入相同体积的生理盐水。记录两组患者直肠温复温时间以及鼻咽温降温、复温时间。结果研究组直肠温复温时间明显短于对照组[(104±30)min vs(127±31)min,P0.05]。研究组和对照组鼻咽温降温时间[(53±10)min vs(57±13)min]、复温时间[(73±20)min vs(84±30)min]差异均无统计学意义。结论硝酸甘油能够缩短深低温停循环心肺转流直肠温的复温时间。
[Abstract]:Objective to investigate the effect of nitroglycerin on the cooling and rewarming of deep hypothermic circulatory arrest cardiopulmonary Bypassa acid (DHC) in deep hypothermia circulatory cardiopulmonary bypass (CPB). Methods 46 patients (male 38, female 8, age 2674 years old) undergoing total aortic arch replacement under DHCAC were randomly divided into study group (n = 24) and control group (n = 22). Both groups were treated with the same temperature change method. The study group received intravenous infusion of nitroglycerin during cooling and rewarming, while the control group received the same volume of normal saline. Rectum rewarming time, nasopharyngeal temperature cooling time and rewarming time were recorded in both groups. Results the rectal rewarming time in the study group was significantly shorter than that in the control group [104 卤30)min vs(127 卤31 min P0.05]. There was no significant difference in nasopharyngeal temperature cooling time (53 卤10)min vs(57 卤13)min) and rewarming time (73 卤20)min vs(84 卤30)min) between the study group and the control group. Conclusion nitroglycerin can shorten the rewarming time of deep hypothermia circulatory cardiopulmonary bypass.
【作者单位】：云南省心血管外科研究所昆明市延安医院心脏大血管外科;
【分类号】：R614

【相似文献】