颅脑损伤后低钠血症患者补充浓氯化钠的临床效果分析

发布时间：2018-05-07 04:04

本文选题：颅脑损伤 + 低钠血症　；参考：《重庆医学》2017年11期

【摘要】：目的探讨颅脑损伤后低钠血症患者采用补充浓氯化钠的临床效果。方法选取2014年2月至2016年2月在该院进行治疗的颅脑损伤后低钠血症患者106例,分为观察组(n=53)和对照组(n=53)。观察组的患者采用补充浓氯化钠的治疗方法,对照组的患者采用常规补充生理需要量进行治疗。比较两组患者的血钠水平恢复时间、血钠纠正率、抗利尿激素分泌失调综合征(SIADH)发生率、病死率及血钠恢复后复发率。结果观察组血症纠正率明显高于对照组(P0.05),血钠平均恢复时间明显少于对照组(P0.05)。两组SIADH发生率、病死率、纠正后复发率比较差异无统计学意义(P0.05)。结论对颅脑损伤后出现低钠血症的患者给予浓氯化钠进行治疗,能够快速地纠正低钠血症,而且不会增加SIADH的发生率,值得推广应用。
[Abstract]:Objective to investigate the clinical effect of sodium chloride supplement in patients with hyponatremia after craniocerebral injury. Methods 106 patients with hyponatremia after craniocerebral injury treated in our hospital from February 2014 to February 2016 were divided into observation group (n = 53) and control group (n = 53). The patients in the observation group were treated with concentrated sodium chloride, while the patients in the control group were treated with routine supplementation of physiological requirements. The recovery time of serum sodium level, the correction rate of serum sodium, the incidence of antidiuretic hormone secretion disorder syndrome (SIADH), the mortality rate and the recurrence rate after the recovery of serum sodium were compared between the two groups. Results the correction rate of blood natrium in the observation group was significantly higher than that in the control group (P 0.05), and the average recovery time of blood sodium in the observation group was significantly lower than that in the control group (P 0.05). There was no significant difference in the incidence, mortality and recurrence rate of SIADH between the two groups (P 0.05). Conclusion the treatment of hyponatremia in patients with hyponatremia after craniocerebral injury can correct hyponatremia quickly without increasing the incidence of SIADH.
【作者单位】：浙江省临安市人民医院神经外科;
【分类号】：R651.15

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