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心脏骤停复苏后患者体温对脑功能预后的影响

发布时间:2018-05-07 23:36

  本文选题:心脏骤停 + 心肺复苏 ; 参考:《临床麻醉学杂志》2016年06期


【摘要】:目的探讨心脏骤停复苏后患者体温与脑功能预后的关系。方法本研究为多中心回顾性队列研究,分析1990年1月1日~2011年12月31日北京市七家三甲医院ICU收治的院内心脏骤停后自主循环恢复超过20min的患者,收集复苏治疗相关数据和其他临床资料,使用脑功能分级(CPC)评估脑功能结局,分析治疗期间体温与脑功能预后的关系。结果共纳入184例患者,其中68例(37.0%)存活至出院,36例(19.6%)出院时脑功能良好(CPC≤2)。35.5℃入ICU后第一个24h内最高体温38.4℃是脑功能预后良好的独立预测因素(OR=8.986,95%CI 1.156~69.882;P=0.036)。结论对于院内心脏骤停后恢复自主循环的患者,入ICU后24h内最高体温维持在35.6~38.3℃有利于脑功能预后。
[Abstract]:Objective to investigate the relationship between body temperature and brain function prognosis after cardiac arrest and resuscitation. Methods from January 1, 1990 to December 31, 2011, a multicenter retrospective cohort study was conducted to analyze the patients who had recovered their autonomic circulation beyond 20min after cardiac arrest in seven third Class A Hospitals in Beijing from January 1, 1990 to December 31, 2011. The data of resuscitation therapy and other clinical data were collected to evaluate the outcome of brain function by using cerebral function grading (CPC) and to analyze the relationship between body temperature and prognosis of brain function during the treatment. Results A total of 184 patients were included, of whom 68 (37. 0) survived to be discharged from hospital (36 / 19. 6) after discharge from ICU, the highest body temperature of 38.4 鈩,

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