单双侧球囊灌注椎体成形治疗老年性椎体压缩骨折的系统评价

发布时间：2018-05-14 15:07

  本文选题：椎体压缩骨折 + 椎体后凸成形术　； 参考：《新疆医科大学》2015年硕士论文

【摘要】：目的：使用系统评价的方法对经皮球囊灌注骨水泥椎体成形单侧入路与双侧入路方法进行分析,以期为椎体后凸成形入路及灌注骨水泥过程中的技术选择提供依据。方法：计算机检索Cochrane Library、PubMed、OVID、Embase、中国生物医学文献数据库、万方数据库、维普资讯等中英文数据库,手工检索9种国内相关杂志,检索日期均从创刊至2014年3月,收集单侧与双侧入路经皮球囊灌注骨水泥椎体后凸成形修复骨质疏松性椎体压缩骨折的随机对照试验,由两名系统评价员按纳入与排除标准选择试验、提取资料和质量评价后,并用RevMan 5.2软件进行Meta分析。结果与结论：最终纳入8个随机对照试验,共507例患者656个椎体。结果显示,骨水泥渗漏方面两组差异无显著性意义；术前目测类比评分[WMD=-0.05(P=0.58)]、短期随访(≤3个月)[WMD=-0.02 (P=0.25)]与长期随访(≥12个月)[WMD=-0.08 (P=0.64)],两组差异无显著性意义；Oswestry功能障碍指数(ODI)短期随访[WMD=-0.13 (P=0.73)]和长期随访[WMD=-0.26 (P=0.81)],两组差异无显著性意义；骨水泥用量和操作时间两组差异有显著性意义,单侧入路较双侧入路有优势；影像学结果中术前、术后后凸角及角度恢复值,差异均无显著性意义提示单侧和双侧入路经皮球囊灌注骨水泥椎体后凸成形修复骨质疏松性椎体压缩骨折,在目测类比评分、影像学结果、并发症方面无明显差异；但在手术时间和放射暴露时间上,单侧入路优于双侧入路。
[Abstract]:Objective: to analyze the unilateral approach and bilateral approach of percutaneous balloon cementation in order to provide a basis for the selection of techniques in the process of kyphoplasty and cementation. Methods: the Chinese and English databases of Cochrane Library PubMeden OVIDB, Chinese Biomedical Literature Database, Wanfang Database and Weipu Information were searched by computer, and 9 domestic related magazines were searched manually from the beginning of publication to March 2014. A randomized controlled trial of unilateral and bilateral approach for the repair of osteoporotic vertebral compression fractures was carried out. The data and quality were extracted and evaluated by two systematic evaluators according to the criteria of inclusion and exclusion. Meta analysis was carried out with RevMan 5.2 software. Results & conclusion: a total of 507 patients with 656 vertebrae were enrolled in 8 randomized controlled trials. The results showed that there was no significant difference in bone cement leakage between the two groups. The preoperative visual analogue score (WMD-0.05), short-term follow-up (鈮，

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