正常人群256CT下头皮灌注参数值范围的定量研究—智能优化算法在大面积颅骨修补术后皮瓣评估的研究及转化应用

发布时间：2018-05-15 03:15

本文选题：CT灌注 + 头皮　；参考：《昆明医科大学》2015年硕士论文

【摘要】：目的：测定正常人群256CT下头皮灌注参数值[组织血容量(TBV)、组织血容量(TBF)、达峰时间(TTP)]范围。材料与方法：选取31例正常人在256 CT下行头皮灌注检查,经肘静脉注射非离子型对比剂碘海醇50 ml,延迟8s后,行灌注检查。用Functional灌注软件包行灌注图像后处理,由两名有经验神经影像诊断医师对图像进行分析,测定额部、颞部、枕部灌注参数值,计算出31例患者头皮灌注参数的平均值及标准差,进一步通过SPSS 17.0进行统计分析得出正常人群头皮灌注正常值范围,并对不同部位灌注值做统计学比较。结果：额部正常值范围为TBF:(25.18-85.66) ml/(100g.min)、TBV:(13.97-55.99) ml/100g、TTP:(16.38-37.82) S;颞部：TBF:(18.39-76.87) ml/(100g.min)、 TBV:(13.42-64.58) ml/100g、TTP (18.79-35.81) S;枕部：TBF:(9.00-37.70) ml/(100g.min)、TBV (10.28-31.96) ml/100g、TTP (26.85-42.85)S。对额部、颞部灌注参数平均值(TBV、TBF、TTP)做两独立样本T检验差异无统计学意义(P0.05),分别对额部与枕部、颞部与枕部的头皮灌注数值做两独立样本T检验,额部、颞部灌注值大于枕部,差异有统计学意义(P0.05)。结论：256CT下测量头皮灌注值为头皮血液动力学的测定提供了一种新的方法,256CT下头皮灌注值范围可以测定头皮血液动力学情况,为进一步解决大面积颅骨修补术后钛网外露奠定了基础。
[Abstract]:Objective: to determine the parameters of scalp perfusion parameters (tissue blood volume (TBV), tissue blood volume (TBF) and peak time (TTP)) under 256CT in normal population. Materials and methods: 31 normal people were examined under 256 CT scalp perfusion, and 50 ml of non ionic contrast agent iodiol was injected by the elbow vein, after delayed 8s, perfusion examination was performed with Functional perfusion. The images were analyzed by two experienced neuroimaging diagnostics, and the parameters of the frontal, temporal and occipital perfusion parameters were measured by two experienced neuroimaging diagnostics. The average value and standard deviation of the scalp perfusion parameters in 31 patients were calculated. The normal range of the normal scalp perfusion in normal population was analyzed by SPSS 17. Results: the range of normal value is TBF: (25.18-85.66) ml/ (100g.min), TBV: (13.97-55.99) ml/100g, TTP: (16.38-37.82) S, and temporal: TBF: (18.39-76.87). /100g, TTP (26.85-42.85) S. (TBV, TBF, TTP) of the frontal and temporal perfusion parameters (TBV, TBF, TTP) did not have statistical significance (P0.05) for two independent samples. The value of the scalp perfusion in the frontal and occipital areas, the temporal and occipital scalp was examined by T, and the value of the frontal and temporal perfusion was greater than that of the occipital region. The difference was statistically significant (P0.05). Conclusion: 256C The measurement of scalp perfusion under T provides a new method for the determination of the hemodynamics of scalp. The range of scalp perfusion value under 256CT can be used to determine the hemodynamics of the scalp, which lays a foundation for further solving the titanium mesh exposure after large area cranioplasty.

【学位授予单位】：昆明医科大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R651.1

【共引文献】