微生态制剂在术后早期炎性肠梗阻治疗中的应用

发布时间：2018-05-28 03:08

本文选题：微生态制剂 + 炎性肠梗阻　；参考：《兰州大学》2017年硕士论文

【摘要】：目的探究微生态制剂辅助治疗术后早期炎性肠梗阻的临床疗效,并再次认识EPII的临床特点。方法回顾性分析兰州大学第一医院2012年1月至2016年6月收治的70例术后早期炎性肠梗阻患者的基本资料,根据在常规治疗的基础上是否应用消化道微生态制剂分为对照组(31例)和干预组(39例)。收集整理两组患者临床资料及随访数据,总结EPII的临床特点,采用SPSS 22.0统计学软件分析两组患者临床疗效及外周血PCT、淋巴细胞计数的变化。结果1、70例患者均保守治愈出院,其中1例发生应激性消化道出血,予以保守治疗后治愈出院。2、术后早期炎性肠梗阻多发生于肠道手术后,保守治疗多有效。3、干预组腹胀消失时间[(2.38±0.59)天]、肠鸣音恢复时间[(5.74±2.91)天]、肛门排气时间[(7.08±3.52)天]和住院时间[(9.44±3.91)天]均较对照组[(2.74±0.51)天]、[(7.84±3.66)天]、[(9.74±4.45)天]、[(12.29±4.91)天]缩短,两组差异有统计学意义(P0.05)。4、两组患者经治疗血清降钙素原均下降,淋巴细胞绝对值均增加,其变化差异有统计学意义(P0.05)。5、70例患者出院后随访3~9个月,失访6例(8.57%),收集到随访资料的64例患者中复发肠梗阻4例(6.25%),无1例手术,仅1例因肠梗阻较重住院保守治疗。结论对于诊断明确的术后早期炎性肠梗阻患者,采用保守治疗的方法多有效;微生态制剂用于术后早期炎性肠梗阻的治疗可缩短治疗时间,促进肠道免疫功能恢复,且使用安全,值得临床推广。
[Abstract]:Objective to explore the clinical effect of microecological preparation in the treatment of early postoperative inflammatory intestinal obstruction and to recognize the clinical characteristics of EPII. Methods the data of 70 patients with early postoperative inflammatory intestinal obstruction treated in the first Hospital of Lanzhou University from January 2012 to June 2016 were retrospectively analyzed. On the basis of routine treatment, the patients were divided into control group (n = 31) and intervention group (n = 39). The clinical data and follow-up data of the two groups were collected, and the clinical characteristics of EPII were summarized. The clinical efficacy, peripheral blood PCT and lymphocyte count of the two groups were analyzed by SPSS 22.0 software. Results (1) 70 patients were cured and discharged, one of them suffered from stress gastrointestinal hemorrhage and was cured after conservative treatment. The early postoperative inflammatory intestinal obstruction occurred mostly after intestinal operation. The duration of abdominal distension disappeared [2.38 卤0.59) days, the recovery time of bowel sounds [5.74 卤2.91] days, the time of anal exhaust [7.08 卤3.52) days] and the hospitalization time [9.44 卤3.91 days] in the intervention group were shorter than those in the control group [2.74 卤0.51) days, [7.84 卤3.66) days], [9.74 卤4.45) days], [12.29 卤4.91) days]. The difference between the two groups was statistically significant (P 0.05N. 4). The serum procalcitonin level decreased and the absolute value of lymphocyte increased in the two groups. The difference was statistically significant in 70 patients with P0.05An. 5The follow-up period was 3 ~ 9 months after discharge. Among 64 patients with recurrent intestinal obstruction, 4 cases had recurrent intestinal obstruction, none had surgery, and only 1 case was treated conservatively because of severe intestinal obstruction. Conclusion the conservative treatment is more effective for the patients with early postoperative inflammatory intestinal obstruction, and the treatment of early postoperative inflammatory intestinal obstruction with microecological preparation can shorten the treatment time and promote the recovery of intestinal immune function. It is safe to use and is worth popularizing in clinic.
【学位授予单位】：兰州大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R656.7

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