益气活血法对膝关节置换术后凝血功能的影响

发布时间：2018-06-08 15:57

本文选题：益气活血法 + 膝关节置换术　；参考：《广东医学》2017年08期

【摘要】：目的研究益气活血药物防治全膝关节表面置换(TKA)术后下肢深静脉血栓(LDVT)的疗效与机制。方法 60例拟行单侧TKA的膝骨关节炎患者,分为观察组和对照组各30例,观察组术后口服益气活血汤联合静脉滴注血栓通,对照组术后口服利伐沙班。观察术后血清D-二聚体、血小板、凝血四项、大腿肿胀率、静脉彩超等。结果两组术后第10天均无LDVT形成。观察组术后第10天的大腿周径小于对照组(P=0.021)。观察组术后第3天的D-二聚体低于对照组(P=0.021)。观察组术后第10天的血小板水平明显高于对照组(P=0.017)。观察组术后第1、10天凝血酶时间均高于对照组(P0.05)。观察组术后第3天纤维蛋白原低于对照组(P=0.049)。结论益气活血中药可有效防治TKA术后LDVT,与口服利伐沙班相比,能够更好地调节术后凝血功能异常,减轻下肢肿胀。
[Abstract]:Objective to study the effect and mechanism of Yiqi Huoxue medicine on the prevention and treatment of deep vein thrombosis (LDVT) after total knee replacement (TKA). Methods 60 patients with unilateral TKA of knee osteoarthritis were divided into observation group and control group, 30 cases in each group. The oral administration of Yiqi Huoxue Decoction Combined with intravenous drip of thrombus after operation, and the control group was taken orally after the operation. The serum D- two polymer, platelets, blood coagulation four, thigh swelling rate and venous color Doppler were observed after operation. Results the two groups had no LDVT formation at tenth days after operation. The thigh diameter of the observation group was less than the control group at tenth days after operation (P=0.021). The D- two body of the observation group was lower than the control group at third days after operation (P=0.021). The platelet level in the observation group was at the tenth day after operation. The time of thrombin in the observation group was higher than the control group (P=0.017) at 1,10 days after operation (P0.05). The fibrinogen of the observation group was lower than the control group (P=0.049) third days after operation (P=0.049). Conclusion Yiqi Huoxue Chinese medicine can effectively prevent and control LDVT after TKA operation. Compared with the oral Lev Shaaban, it can better regulate the abnormal coagulation function and reduce the lower extremity after the operation. Swollen.
【作者单位】：广东省第二中医院骨伤一科;
【基金】：广东省中医药局建设中医药强省科研课题(编号:20141036)
【分类号】：R687.4

【相似文献】