聚桂醇内痔区注射治疗出血性内痔的临床对比研究

发布时间：2018-06-24 17:40

本文选题：聚桂醇 + 出血性内痔　；参考：《广西医科大学》2017年硕士论文

【摘要】：目的:通过对比研究的方式,将传统的消痔灵内痔注射治疗与聚桂醇内痔注射治疗两种药物注射治疗进行比较,探讨聚桂醇注射治疗的优缺点。方法:通过对比分析2015年1月到2016年1月年我院收治并行注射治疗的内痔患者216例,其中试验组114例,对照组102例。把两组患者按照一下指标进行对比分析:治疗疗效、肛门疼痛评分、复发率、肛门坠胀、排便困难、便血。结果:随访3个月,随访反馈显示:1.注射试验组治疗后疗效优于对照组,有统计学意义(痔核消失P值为0. 043);2.注射试验组治疗后平均疼痛评分低于对照组,有统计学意义(P值为0. 046);3.试验组出现肛门坠胀56例,对照组74例,试验组占优势。差异有统计学意义(x2=4.307 P=0.038);4.试验组有2例复发,对照组有12例复发。两组患者1月、2月总复发率有差异,试验组低于对照组(P0.05.差异无统计学意义);3月总复发率试验组比对照组低(P0.05,差异有统计学意义);5.两组患者均未出现肛门狭窄、肛门失禁等。结论:1.聚桂醇注射治疗出血性内痔较传统硬化剂疗效肯定;2.聚桂醇注射治疗出血性内痔较传统硬化剂比较,患者疼痛感轻;3.聚桂醇注射治疗后肛门坠胀发生率较传统消痔灵发生率低,注射后便血、排便困难均无发生;4.聚桂醇注射后第1个月和第2个月复发率试验组低于对照组,但差异无统计学意义,注射3个月的随访过程中,试验组复发率低于对照组,差异有统计学意义,聚桂醇注射治疗远期复发率优于消痔灵注射液。
[Abstract]:Aim: to compare the traditional injection therapy of Xiaozhiling and polycinnamol injection for internal hemorrhoids, and to discuss the advantages and disadvantages of the injection of polycinnamol. Methods: 216 cases of internal hemorrhoids treated with injection from January 2015 to January 2016 were analyzed, including 114 cases in the experimental group and 102 cases in the control group. The two groups were compared and analyzed according to the following indexes: curative effect, anal pain score, recurrence rate, anal distension, defecation difficulty, blood stool. Results: follow up 3 months, follow-up feedback showed 1. 1. The therapeutic effect of injection test group was better than that of control group (P = 0. 0). 043) The average pain score in the injection group was significantly lower than that in the control group (P = 0. 05). 046) There were 56 cases of anal bloating in the test group and 74 cases in the control group. The difference was statistically significant (x2 + 4.307 P0. 038). Two cases recurred in the trial group and 12 cases in the control group. There was a difference in the total recurrence rate between the two groups in 1 month and 2 months, which was lower in the trial group than in the control group (P 0.05). The total recurrence rate of 3 months in the trial group was lower than that in the control group (P0. 05, the difference was statistically significant). There was no anal stricture or anal incontinence in both groups. Conclusion 1. Injection of polycinnamol in the treatment of hemorrhagic hemorrhoids is more effective than traditional sclerosing agent. Injection of polycinnamol in the treatment of hemorrhagic hemorrhoids compared with traditional sclerosing agents, patients with mild pain. The incidence of anus drop distention after injection of polycinnamol was lower than that of traditional Xiaozhiling. The relapse rate of the experimental group was lower than that of the control group at the 1st and 2nd month after injection, but the difference was not statistically significant. The recurrence rate of the trial group was lower than that of the control group during the follow-up of 3 months after injection, and the difference was statistically significant. The long-term recurrence rate of polycinnamol injection was better than that of Xiaozhiling injection.
【学位授予单位】：广西医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R657.18

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