关节置换术患者手术部位感染危险因素的荟萃分析

发布时间：2018-06-25 01:22

本文选题：关节置换术 + 手术部位感染　；参考：《中华医院感染学杂志》2017年18期

【摘要】：目的分析关节置换(TJR)患者发生手术部位感染(SSI)的危险因素,为制定感染控制策略提供依据。方法计算机检索CNKI、万方、VIP、CBM、Pubmed、Embase、Web of Science、Cochrane数据库文献,由两名评价员根据纳入及排除标准独立筛选文献、提取数据和质量评价后,用RevMan5.3软件进行荟萃分析。结果纳入18篇文献,关节置换患者3479例,合并手术部位感染798例。荟萃分析结果显示:长期使用激素(OR=4.46)、有关节手术史(OR=4.14)、合并非手术区域感染(OR=9.42)、术后伤口血肿或开裂(OR=5.62)、手术时间长(SMD=0.93)是TJR患者发生SSI的重要危险因素(P0.05)。结论 TJR患者发生SSI的危险因素纷繁复杂,只有对相关危险因素进行综合干预,才能有效预防和控制感染的发生。
[Abstract]:Objective to analyze the risk factors of surgical site infection (SSI) in patients with joint replacement (TJR). Methods the CNKI, VIPC, CBM, Pubmed Embase, Web of Science and Cochrane databases were searched by computer. The two evaluators independently screened the literatures according to the inclusion and exclusion criteria. After extracting the data and evaluating the quality, the data were collected and the meta-analysis was carried out with Revman 5.3 software. Results 3479 patients with joint replacement and 798 patients with surgical site infection were included in 18 articles. The results of meta-analysis showed that long-term use of hormone (OR4.46), history of joint surgery (OR4.14), infection of non-operative area (OR9.42), postoperative wound hematoma or dehiscence (OR5.62), and long operation time (SMD0.93) were important risk factors for SSI in TJR patients (P0.05). Conclusion the risk factors of SSI in TJR patients are numerous and complicated. Only by comprehensive intervention of related risk factors can the occurrence of infection be effectively prevented and controlled.
【作者单位】：遵义医学院附属医院感染科;遵义医学院附属医院关节外科;遵义医学院附属医院医院感染管理科;
【基金】：贵州省科学技术基金资助项目(黔科合J字2010-2182)
【分类号】：R687.4

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