铁代谢指标与术后认知功能障碍关系初探

发布时间：2018-06-27 18:15

本文选题：铁代谢 + 血清铁蛋白　；参考：《中国地方病防治杂志》2017年02期

【摘要】：目的初步探讨术后认知功能障碍(POCD)患者的铁代谢指标变化。方法手术全麻患者60例根据各时点MMSE评分分为对照组(C组)和POCD组(P组)。于术前(T1)、术后1(T2)、3(T3)、7 d(T4)检测MMSE评分、血清铁蛋白(SF)、血清转铁蛋白(TF)、血清铁、转铁蛋白饱和度(TS)水平。结果与C组或T1比较,P组患者T2-4时点的SF、TS、血清铁均升高,TF降低(P0.05)。结论在术后早期(1~7 d)发生POCD患者铁代谢表现为SF、血清铁、TS升高,TF降低。
[Abstract]:Objective to investigate the changes of iron metabolism in patients with cognitive dysfunction (POCD) after operation. Methods 60 patients with general anesthesia were divided into control group (group C) and POCD group (P group) according to MMSE scores at different time points. MMSE score, serum ferritin (SF), serum transferrin (TF), serum iron and transferrin saturation (TS) were measured before operation (T1) and 1 (T2) / 3 (T3) / 7d (T4). Results compared with group C or T _ 1, the serum iron levels of SFN TSS-T _ 2-4 in P group were significantly higher than those in T _ 1 group (P 0.05). Conclusion the iron metabolism of POCD patients in the early postoperative period (1 ~ 7 days) was SF.Serum iron TS increased and TF decreased.
【作者单位】：河北医科大学第一医院麻醉科;五矿邯邢职工总医院重症监护室;
【基金】：河北省卫生厅计划项目(编号ZD20140451)
【分类号】：R614.2

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