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乳腺癌术后发热患者血清降钙素原检测及临床意义

发布时间:2018-07-02 14:20

  本文选题:乳腺癌 + 术后发热 ; 参考:《实用癌症杂志》2016年12期


【摘要】:目的探讨检测血清降钙素原在乳腺癌术后发热患者中的变化,并分析其临床应用价值。方法采取回顾性方法对80例乳腺癌发热的患者临床资料进行分析,且依据患者的临床症状与病原学的检查情况将其分为病原学阳性组与发热原因不明组以及临床诊断感染组,检测3组血清中降钙素原的表达水平,分析其临床应用价值。结果病原学阳性组降钙素原含量为(7.8±2.1)ng/m L,临床诊断感染组降钙素原含量为(2.6±0.6)ng/m L,发热原因不明组降钙素原含量为(0.5±0.1)ng/m L,3组间数据比较,差异有统计学意义(P0.05)。不同年龄、是否绝经、是否淋巴结转移和发热程度以及不同化疗方案各组中≤0.5 ng/m L、0.5~2.0 ng/m L、2.1~10.0 ng/m L、10.0 ng/m L的比例比较,差异无统计学意义(P0.05)。病原学阳性组降钙素原含量阳性表达率高于临床诊断感染组、发热原因不明组,3组降钙素原阳性表达率比较,差异有统计学意义(P0.05)。结论临床中检测血清中降钙素原对乳腺癌术后发热性质能进行较好地鉴别与诊断,且该指标检测并不受患者的年龄和绝经状况以及淋巴结是否转移与发热程度以及不同化疗方案等因素影响,临床应用价值高。
[Abstract]:Objective to investigate the changes of serum procalcitonin in patients with postoperative fever of breast cancer and to analyze its clinical value. Methods the clinical data of 80 patients with breast cancer fever were analyzed retrospectively. According to the clinical symptoms and etiology of the patients, the patients were divided into three groups: etiology positive group, fever unknown group and clinical infection group. The expression of procalcitonin in serum of three groups was detected and its clinical application value was analyzed. Results the content of procalcitonin was (7.8 卤2.1) ng/m / L in the positive group, (2.6 卤0.6) ng/m / L in the clinically diagnosed infection group and (0.5 卤0.1) ng/m / L in the group with unknown fever cause. The difference was statistically significant (P0.05). There was no significant difference between different age, menopause, lymph node metastasis and fever, and the proportion of 鈮,

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