经皮椎体后凸成形术联合痿痹消治疗骨质疏松性椎体压缩性骨折的临床疗效研究

发布时间：2018-07-09 19:49

本文选题：经皮椎体后凸成形术 + 痿痹消　；参考：《安徽中医药大学》2017年硕士论文

【摘要】：目的:观察与探讨经皮椎体后凸成形术联合中药痿痹消治疗骨质疏松性椎体压缩性骨折的临床疗效,通过评估对照组和观察组的差异和不同,说明经皮椎体后凸成形术联合痿痹消治疗骨质疏松性椎体压缩性骨折优于单纯行经皮椎体后凸成形术。方法:收集并整理2015年3月~2016年3月于安徽中医药大学第一附属医院骨科住院的60例骨质疏松性椎体压缩性骨折患者,采取前瞻性研究,将患者随机分为两组即观察组和对照组,每组30例,对照组患者单纯行经皮椎体后凸成形术来治疗,观察组患者在行经皮椎体后凸成形术后予以中药痿痹消内服,服药时间为1个月,术后随访时间不少于3个月,对两组患者的VAS评分、Oswestry功能指数和临床效果进行评估。结果:(1)两组患者的性别、年龄、骨折节段等一般基线资料,差异均无统计学意义(p0.05),具有可比性。(2)治疗前,两组患者的VAS评分和Oswestry功能指数,差异均无统计学意义(p0.05),具有可比性。(3)VAS评分比较:术后两组患者评分均明显降低,术后各时间点与术前相比较,差异有统计学意义(p0.05);治疗2天后比较,差异无统计学意义(p0.05);治疗1个月后比较,差异有统计学意义(p0.05);治疗3个月后比较,观察组疼痛评分明显降低,差异有统计学意义(p0.05);表明治疗2天后即短期内经皮椎体后凸成形术止痛效果较好,治疗1个月后观察组疼痛缓解优于对照组,治疗3个月后观察组疼痛明显缓解且较为理想。(4)Oswestry功能指数比较:术后各时间点与术前相比较,评分均明显降低,差异有统计学意义(p0.05);治疗2天后比较,差异无统计学意义(p0.05);治疗1个月后比较,差异无统计学意义(p0.05);治疗3个月后比较,差异有统计学意义(p0.05);表明两组术后患者功能活动均有改善,治疗3个月后,观察组的功能活动恢复明显优于对照组。(5)观察组的临床总有效率为96.67%,对照组为90.00%,差异具有统计学意义(p0.05)。结论:经皮椎体后凸成形术联合中药痿痹消治疗骨质疏松性椎体压缩性骨折疗效较好,明显优于单纯行经皮椎体后凸成形术进行治疗。联合用药时止痛效果更好,并且可促进腰椎活动功能的恢复,临床值得推广使用。
[Abstract]:Objective: to observe and explore the clinical effect of percutaneous kyphoplasty combined with traditional Chinese medicine Bubixiao in the treatment of osteoporotic vertebral compression fracture, and to evaluate the difference and difference between the control group and the observation group. The results showed that percutaneous kyphoplasty combined with impotence was superior to percutaneous kyphoplasty in the treatment of osteoporotic vertebral compression fracture. Methods: from March 2015 to March 2016, 60 patients with osteoporotic vertebral compression fractures in the Department of Orthopaedics, the first affiliated Hospital of Anhui University of traditional Chinese Medicine, were collected and analyzed. The patients were randomly divided into two groups: observation group (n = 30) and control group (n = 30). Patients in control group were treated with percutaneous kyphoplasty. The time of taking medicine was 1 month and the follow-up time was not less than 3 months. The VAS score and Oswestry function index and clinical effect were evaluated in both groups. Results: (1) there was no significant difference in baseline data of sex, age and fracture segment between the two groups (p0.05). (2) the VAS score and Oswestry function index of the two groups before treatment were comparable. (3) comparison of VAS scores: the scores of the two groups were significantly lower than those of the patients before operation (p0.05), the difference was statistically significant (p0.05) after 2 days of treatment, the difference between the two groups was significant (p0.05), the difference was statistically significant (p0.05), and the difference was significant after 2 days of treatment. The difference was not statistically significant (p0.05), the difference was statistically significant after one month of treatment (p0.05), and the pain score of the observation group was significantly lower than that of the control group after 3 months of treatment. The difference was statistically significant (p0.05), which indicated that the pain relief of the observation group was better than that of the control group after 2 days of treatment, and the effect of percutaneous kyphoplasty was better than that of the control group. (4) comparison of Oswestry function index: the scores of all postoperative time points were significantly lower than those before operation (p0.05), and after 2 days of treatment, the scores were significantly lower than those before treatment (p0.05), and after 2 days of treatment, the scores of Oswestry function index were significantly lower than those of before treatment (p0.05). The difference was not statistically significant (p0.05); after one month of treatment, there was no significant difference (p0.05); after 3 months of treatment, the difference was statistically significant (p0.05). The recovery of functional activity in the observation group was significantly better than that in the control group. (5) the total clinical effective rate of the observation group was 96.67 and that of the control group was 90.000.The difference was statistically significant (p0.05). Conclusion: percutaneous kyphoplasty combined with traditional Chinese medicine Bixiao is effective in the treatment of osteoporotic vertebral compression fracture, which is superior to percutaneous kyphoplasty alone. The combined therapy has better analgesic effect and can promote the recovery of lumbar motor function, so it is worth popularizing in clinic.
【学位授予单位】：安徽中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R687.3

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