舒芬太尼在老年结肠癌术后的应用对SOFA评分的影响

发布时间：2018-07-25 17:11

【摘要】：目的评价舒芬太尼在老年高血压结肠癌根治术后应用对SOFA评分的影响,并与芬太尼比较。方法选取武汉市第一医院择期行结肠癌手术治疗的老年高血压患者,随机分为舒芬太尼组与芬太尼组,术后给予镇痛治疗,舒芬太尼0.1~0.2μg/(kg·h)维持;芬太尼组:0.5~2.0μg/(kg·h)维持,比较各时间点的SOFA评分。结果舒芬太尼组内比较:术后入ICU后SOFA评分与各时间点SOFA评分比较,差异具有统计学意义(P0.05)。芬太尼组内比较:术后入ICU后SOFA评分与术后48和72 h的SOFA评分差异具有统计学意义(P0.05);术后入ICU后SOFA评分与术后24 h的评分差异不具有统计学意义(P0.05)。两组组间比较:与芬太尼组术后SOFA评分比较,舒芬太尼组术后24、48和72 h SOFA评分差异具有统计学意义(P0.05)。结论舒芬太尼用于重症患者具有良好的镇痛作用;舒芬太尼对重症患者术后SOFA评分的改变效果显著。
[Abstract]:Objective to evaluate the effect of sufentanil on SOFA score after radical resection of hypertensive colon cancer in elderly patients and compare it with fentanyl. Methods elderly patients with hypertension undergoing elective colon cancer surgery in the first Hospital of Wuhan City were randomly divided into sufentanil group and fentanyl group. Postoperative analgesia was given, sufentanil 0.1 渭 g / (kg h) was maintained, fentanyl group was maintained at 2.0 渭 g / (kg h). The SOFA scores at each time point were compared. Results in sufentanil group, there was significant difference between SOFA score and SOFA score after ICU (P0.05). Comparison of fentanyl group: the SOFA score after ICU was significantly different from the SOFA score at 48 and 72 hours after operation (P0.05), but the SOFA score after ICU had no significant difference with that at 24 hours after operation (P0.05). Comparison between the two groups: compared with the SOFA score of fentanyl group, the SOFA score of sufentanil group was significantly higher than that of fentanyl group at 24 ~ 48 and 72 hours postoperatively (P0.05). Conclusion Sufentanil has a good analgesic effect on severe patients, and sufentanil has a significant effect on the change of SOFA score after operation.
【作者单位】：湖北省武汉市第一医院重症医学科;
【分类号】：R614;R735.35

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