咪达唑仑联合丙泊酚靶控输注静脉镇静对拔除下颌第三磨牙患者焦虑水平的影响

发布时间：2018-07-25 18:59

【摘要】：目的:研究咪达唑仑联合丙泊酚靶控输注(target controlled infusion,TCI)静脉镇静对拔除下颌第三磨牙患者在围手术期焦虑水平的影响。方法:选择北京大学口腔医院拔除下颌阻生第三磨牙,在初次就诊时状态焦虑量表(state anxiety inventory,SAI)得分≥38分的患者,根据是否于静脉镇静下拔牙分为静脉镇静+局部麻醉组(intravenous sedation,IVS)和局部麻醉组(local anesthesia,LA)。每组患者再根据初次就诊时的SAI评分分为两个亚组:IVS-Ⅰ、LA-Ⅰ(SAI得分38~50)和IVS-Ⅱ、LA-Ⅱ(SAI得分51~80)。根据患者在初诊(T1)、手术前(T2)和手术后7 d(T3)时SAI评分,评价患者在手术前后的焦虑情况。通过观察患者术中的心率、血压和疼痛视觉模拟评分(visual analogue scale,VAS)评价患者手术中的焦虑情况。结果:IVS组和LA组在T1、T2、T3时的SAI评分差异无统计学意义(P0.05),IVS组在术中的心率、血压和VAS疼痛评分显著低于LA组(P0.001)。结论:咪达唑仑联合丙泊酚靶控输注静脉镇静可以显著降低拔除下颌第三磨牙患者术中的焦虑,提高手术的舒适性,使心率、血压、血氧饱和度维持在正常水平。但对比两组患者的SAI评分发现,静脉镇静对初诊(T1)、手术前(T2)、手术后7d(T3)的焦虑水平无明显影响。
[Abstract]:Aim: to study the effect of intravenous sedation with midazolam combined with propofol target controlled infusion of (target controlled on the perioperative anxiety of patients with mandibular third molar extraction. Methods: patients with mandibular impacted third molar were selected from Peking University Stomatology Hospital and scored more than 38 points in (state anxiety inventory scale (SAI) at the first visit. According to whether the teeth were extracted under intravenous sedation, they were divided into intravenous sedative group and local anesthesia group. Each group was further divided into two subgroups according to the SAI score of the first visit: 1: IVS- 鈪，

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