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急性时相蛋白、降钙素原及免疫指标在膝关节置换术后早期感染患者中的检测意义

发布时间:2018-07-31 08:33
【摘要】:目的探讨急性时相蛋白、降钙素原及免疫指标在膝关节置换术后早期感染患者中的检测意义,为该类手术患者早期感染的诊断提供依据。方法将2014年12月-2016年5月医院收治的36例膝关节置换术后早期感染设为A组,同时期的36例未发生感染的膝关节置换术患者为B组,36名健康人员为C组,比较3组受试人员的血清急性时相蛋白、降钙素原及免疫指标,并比较A组浅层感染和深部感染患者的上述检测指标。结果 A组的血清急性时相蛋白指标CRP、α1-AT、CER及α1-AG水平分别为(6.12±0.59)mg/L、(3.12±0.22)g/L、(564.24±32.78)mg/L及(118.98±12.45)mg/dl,其分别高于B组的(4.78±0.49)mg/L、(1.63±0.15)g/L、(419.78±28.75)mg/L、(92.34±9.73)mg/dl及C组的(2.21±0.25)mg/L、(0.59±0.05)g/L、(271.63±25.38)mg/L、(59.69±5.34)mg/dl,B组则高于C组;A组的血清降钙素原高于B组及C组,B组则高于C组;免疫指标A组差于B组及C组B组则差于C组,且A组深部感染患者则差于浅层感染患者,差异均有统计学意义(P0.05)。结论急性时相蛋白、降钙素原及免疫指标在膝关节置换术后早期感染患者中的检测意义较高,对于感染的早期检测及感染情况的了解均有较高的价值。
[Abstract]:Objective to investigate the significance of detection of acute phase proteins, procalcitonin and immune markers in early infection patients after knee arthroplasty, and to provide evidence for the diagnosis of early infection in patients undergoing knee arthroplasty. Methods from December 2014 to May 2016, 36 patients with early infection after knee arthroplasty in our hospital were divided into group A and group C with 36 patients without infection in the same period. The serum levels of acute phase protein, procalcitonin and immunological indexes were compared among the three groups, and those of the patients with superficial infection and deep infection in group A were compared. 缁撴灉 A缁勭殑琛,

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