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心肺转流下心脏瓣膜术后急性肾损伤的危险因素分析

发布时间:2018-08-03 18:57
【摘要】:目的探讨成人心肺转流(cardiopulmonary bypass,CPB)下心脏瓣膜手术后急性肾损伤(acute kidney injury,AKI)的危险因素。方法回顾性分析1 349例心脏瓣膜手术患者的临床资料,采用多因素Logistic回归分析心脏瓣膜术后AKI的危险因素。结果 1 349例心脏瓣膜手术患者AKI发生率为28.4%,多因素Logistic回归分析显示,每增加1岁(OR=1.05,95%CI 1.03~1.06,P0.001)、糖尿病史(OR=2.11,95%CI 1.22~3.68,P=0.008)、贫血(OR=1.50,95%CI1.05~2.21,P=0.026)、术前血清肌酐(Scr)值每增加1mg/dl(OR=1.01,95%CI 1.01~1.02,P=0.001)、手术时间每增加1h(OR=1.28,95%CI 1.15~1.41,P0.001)、术中输注血浆(OR=1.50,95%CI 1.14~1.97,P=0.004)是心脏瓣膜术后发生AKI的独立危险因素。结论心肺转流下心脏瓣膜术后急性肾损伤的独立危险因素是高龄、糖尿病史、贫血、术前肌酐高、手术时间长以及术中输注血浆。
[Abstract]:Objective to investigate the risk factors of acute renal injury (acute kidney injury-AKI) after cardiac valve surgery in adult patients with cardiopulmonary bypass (cardiopulmonary). Methods the clinical data of 1 349 patients undergoing cardiac valve surgery were retrospectively analyzed. Multivariate Logistic regression analysis was used to analyze the risk factors of AKI after cardiac valve surgery. Results the incidence of AKI in 1 349 patients undergoing cardiac valve surgery was 28. 4%. Multivariate Logistic regression analysis showed that the incidence of AKI was 28. 4%. 姣忓鍔,

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