脊柱外科患者医院感染的病原菌分布及耐药性分析

发布时间：2018-08-04 20:09

【摘要】：目的分析脊柱外科患者医院感染的病原菌分布及耐药性,为其预防和控制提供理论依据。方法回顾性分析2013年1月-2016年1月脊柱外科患者3 702例的临床资料,主要包括不同疾病的医院感染率、感染部位、感染菌株等;对发生医院感染患者的病原菌分布及耐药性进行检测。结果有36例患者发生医院感染,医院感染率为0.97%;感染部位以呼吸道为主,共21例占58.33%;共分离出病原菌154株,以革兰阴性菌为主,共106株占68.83%;铜绿假单胞菌、大肠埃希菌、肺炎克雷伯菌对氨苄西林耐药率较高,均70.00%;金黄色葡萄球菌、表皮葡萄球菌对青霉素G、红霉素耐药率较高,均80.00%。结论脊柱外科患者医院感染的病原菌分布及耐药性有一定的特点,临床医务人员根据药敏试验结果选取合理抗菌药物,能显著降低医院感染率、提高手术效果。
[Abstract]:Objective to analyze the distribution and drug resistance of nosocomial infection in spinal surgery patients, and to provide theoretical basis for prevention and control of nosocomial infection. Methods the clinical data of 3 702 cases of spinal surgery from January 2013 to January 2016 were analyzed retrospectively, including nosocomial infection rate, infection site and infection strains of different diseases. The distribution and drug resistance of pathogenic bacteria in patients with nosocomial infection were detected. Results the nosocomial infection occurred in 36 patients, the nosocomial infection rate was 0.97; the infection site was mainly respiratory tract, 21 cases were 58.33.The pathogenic bacteria were 154 strains, 106 strains were Gram-negative bacteria (68.83%), Pseudomonas aeruginosa, Escherichia coli, The resistant rate of Klebsiella pneumoniae to ampicillin was higher than that of Staphylococcus aureus and Staphylococcus epidermidis to penicillin G and erythromycin. Conclusion the distribution of pathogens and drug resistance in spinal surgery patients with nosocomial infection have certain characteristics. According to the results of drug sensitivity test, the reasonable antibiotics can significantly reduce the nosocomial infection rate and improve the surgical effect.
【作者单位】：商丘市第一人民医院骨一科;
【分类号】：R687

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