54例肉瘤患者回顾性分析及典型病例探讨

发布时间：2018-08-11 08:37

【摘要】：目的：通过回顾性研究分析我院肉瘤患者一般资料、临床特征、治疗方式、中医证型及转归,为以后的科学研究提出思路和方向。方法：采用回顾性研究的方法,收集自2009年3月1日至2015年3月1日东方医院肿瘤科病理诊断为肉瘤的住院患者病例。记录其一般情况、肿瘤诊断信息、病史资料、治疗情况及转归。应用SPSS软件进行统计分析。结果：共收集到肉瘤患者54例,占我科6年间收治所有恶性肿瘤患者的1.41%,其中男26例,女28例。我院最常见的是平滑肌肉瘤,其次是纤维肉瘤、脂肪肉瘤。不同病理类型在不同性别间有显著差异。肿瘤部位上最常见为内脏原发的肉瘤,其次为四肢。患者绝大多数为临床Ⅲ期、Ⅳ期。最普遍的转移部位是淋巴结,其次是肺,但肺转移独立出现的几率更高。在治疗上,多数患者接受手术治疗,仅2例患者接受靶向治疗。氩氦刀与中药治疗作为我科特色被大部分患者接受,未失访的7例患者平均治疗后生存期为16.57个月,其中2例患者死亡,5例患者仍继续在院治疗。接受其他治疗的4例患者平均治疗后生存期为2.75个月。典型病例为Ⅳ期骨肉瘤外院多重治疗后进展患者,经氩氦刀联合中药治疗治疗后生存19个月,疗效显著。结论：我院收治肉瘤患者总体发病率与文献相符,但以临床Ⅲ期、Ⅳ期为主,病理类型及转移部位与文献报道有差异,这与我科氩氦刀联合中药的特色治疗密切相关。氩氦刀联合中药治疗的患者生存期相较于应用其他治疗患者有更长的趋势,典型个案生存期相较文献延长。氩氦刀联合中药的治疗模式值得进一步研究。
[Abstract]:Objective: to analyze the general data, clinical characteristics, treatment methods, TCM syndromes and prognosis of sarcoma patients in our hospital. Methods: from March 1, 2009 to March 1, 2015, inpatients with sarcoma diagnosed by pathology in Department of Oncology, Oriental Hospital, were collected by retrospective study. Record its general information, tumor diagnosis information, medical history, treatment and outcome. SPSS software was used for statistical analysis. Results: a total of 54 cases of sarcoma were collected, accounting for 1.41% of all patients with malignant tumor treated in our department during the past 6 years, including 26 cases of males and 28 cases of females. Leiomyosarcoma is the most common in our hospital, followed by fibrosarcoma and liposarcoma. There were significant differences in different pathological types between sexes. Visceral primary sarcoma was the most common tumor, followed by limbs. Most of the patients were stage 鈪，

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