膝骨性关节炎疼痛与骨髓水肿MRI影像学改变的相关性

发布时间：2018-08-17 18:36

【摘要】：目的:探讨膝骨性关节炎(KOA)疼痛程度与MRI软骨下骨髓水肿(BME)程度的相关性。方法:KOA 142例按疼痛程度分为无疼痛组31例、疼痛1级组86例、疼痛2级组25例,将其MRI骨髓水肿分为0级(无骨髓水肿)38例、1级(轻度骨髓水肿)69例、2级(较大骨髓水肿)35例,将疼痛程度与KOA骨髓水肿分级进行χ2检验,并将疼痛各组与水肿分级进行多个独立样本比较的秩和检验。结果:无疼痛组29.1%(9/31例)存在BME,疼痛1级组82.6%(71/86例)存在BME,疼痛2级组92%(24/25例)存在BME;无疼痛组与疼痛1级组、疼痛2级组相比差异有统计学意义(χ2=12.613,P0.001;χ2=14.535,P0.001),多个独立样本比较的秩和检验显示,3组BME差异有统计学意义(P0.001),随疼痛的加重,BME分级的平均秩次逐渐加大(0级、1级和2级分别为79.12、102.82和139.26)。结论:KOA疼痛与软骨下骨髓水肿相关,且存在疼痛越重、骨髓水肿越严重的趋势。
[Abstract]:Objective: to investigate the correlation between (KOA) pain and (BME) degree of MRI subchondral bone marrow edema in knee osteoarthritis. Methods according to the degree of pain, 142 cases were divided into pain free group (n = 31), pain grade 1 group (n = 86) and pain grade 2 group (n = 25). MRI bone marrow edema was divided into 0 grade (without bone marrow edema), 38 cases with grade 1 (mild bone marrow edema) and 69 cases with large bone marrow edema (large bone marrow edema). The degree of pain and the grade of bone marrow edema in KOA were tested by 蠂 2 test, and the rank sum test was used to compare the pain degree with the grade of edema in multiple independent samples. Results: BMEwas present in 29.1% (9 / 31 cases) of the pain free group, 82.6% (71 / 86 cases) in the pain grade 1 group, 92% (24 / 25 cases) in the pain grade 2 group, and 2% (24 / 25 cases) in the pain free group and the pain grade 1 group. There was a significant difference between the two groups (蠂 2 + 12.613 P 0.001; 蠂 2 + 14.535% P 0.001). The rank sum test of multiple independent samples showed that there was a significant difference in BME between the three groups (P0. 001). The average rank of BME grade increased gradually with the exacerbation of pain (0 grade 1 and 2 grade 79.12102.82 and 139.26 respectively). ConclusionThe weight KOA pain is associated with subchondral bone marrow edema, and the more severe the pain, the more serious the bone marrow edema.
【作者单位】：青海大学附属医院关节骨病科;
【分类号】：R684.3;R445.2

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