间叶性软骨肉瘤156例文献综合分析

发布时间：2018-08-22 20:29

【摘要】：目的探讨间叶性软骨肉瘤的临床及病理特点,提高对该病的诊治水平。方法利用中国医院知识数据库检索题名为"间叶性软骨肉瘤"或"间叶型软骨肉瘤"的1994至2015年文献,去除重复病例,收集整理并分析经病理确诊为间叶性软骨肉瘤的病例。结果检索到文献81篇,收集间叶性软骨肉瘤病例156例,男女比例为1:1.26,年龄11个月至72岁,平均年龄31.5岁,病变原发于骨91例,骨外软组织65例。主要表现为肿大包块压迫及疼痛,影像学表现为溶骨性破坏及软组织包块点片样钙化,病理特点为间变未分化间叶细胞与分化较好的肿瘤性软骨双相并存,生物学行为多生长缓慢但容易复发转移,治疗以广泛扩大切除为主。结论间叶性软骨肉瘤确诊需病理,治疗以手术为主。
[Abstract]:Objective to investigate the clinical and pathological features of mesenchymal chondrosarcoma and to improve the diagnosis and treatment of the disease. Methods Chinese hospital knowledge database was used to search the literature of "mesenchymal chondrosarcoma" or "mesenchymal chondrosarcoma" from 1994 to 2015, to remove repeated cases and to collect and analyze the cases of mesenchymal chondrosarcoma confirmed by pathology. Results among 81 literatures, 156 cases of mesenchymal chondrosarcoma were collected. The ratio of male to female was 1: 1.26. The age ranged from 11 months to 72 years, with an average age of 31.5 years. The lesions originated in 91 cases of bone and 65 cases of soft tissue outside bone. The main manifestations were compression and pain of swelling mass, osteolytic destruction and spot calcification of soft tissue mass. The pathological features were that the undifferentiated mesenchymal cells co-existed with the well-differentiated tumor cartilage. Biological behavior grows slowly but is easy to recur and metastasize. Extensive excision is the main treatment. Conclusion the diagnosis of mesenchymal chondrosarcoma needs pathology and surgical treatment.
【作者单位】：解放军第89医院血液肿瘤科;
【分类号】：R738

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