月经周期不同阶段对妇科腹腔镜手术后恶心呕吐的影响

发布时间：2018-09-12 09:41

【摘要】：目的观察月经周期不同阶段对妇科腹腔镜手术后恶心呕吐(PONV)的影响。方法选择2016年3月至2017年2月在北京大学第一医院接受全身麻醉下妇科腹腔镜手术的患者228例。根据患者在手术日处于月经周期的不同阶段分为卵泡期(n=98)、排卵期(n=79)和黄体期(n=51)。收集围术期资料,记录术后0~2h、0~24h内恶心呕吐的发生情况。采用Logistic回归模型分析月经周期不同阶段对PONV发生率的影响。结果术后0~2h有53例(23.2%)患者发生PONV,0~24h有125例(54.8%)PONV。单因素分析显示:月经周期不同阶段PONV发生率差异无统计学意义。多因素Logistic回归分析显示:手术时间1h(OR=3.176,95%CI 1.567~6.436,P=0.001)、PONV史(OR=5.711,95%CI 1.710~19.080,P=0.005)是术后0~2h恶心呕吐的独立危险因素;手术时间1h(OR=2.577,95%CI 1.460~4.549,P=0.001)、术后使用PCA泵(OR=2.671,95%CI 1.224~5.831,P=0.014)、术后应用甲硝唑(OR=2.728,95%CI 1.413~5.267,P=0.003)是术后0~24h恶心呕吐的独立危险因素。结论月经周期不同阶段对妇科腹腔镜手术后恶心呕吐的发生率无明显影响。
[Abstract]:Objective to observe the effect of different periods of menstrual cycle on (PONV) of nausea and vomiting after gynecological laparoscopy. Methods 228 patients undergoing gynecologic laparoscopic surgery under general anesthesia were selected from March 2016 to February 2017 in the first Hospital of Peking University. According to the different stages of menstrual cycle on the day of operation, the patients were divided into follicular stage (nm98), ovulation stage (nm79) and luteal phase (N51). The data of perioperative period were collected to record the incidence of nausea and vomiting within 2 hours and 24 hours after operation. Logistic regression model was used to analyze the influence of different periods of menstrual cycle on the incidence of PONV. Results there were 53 cases (23.2%) with PONV,0~24h at 0 h after operation, 125 cases (54.8%) with PONV.. Univariate analysis showed that there was no significant difference in the incidence of PONV in different stages of menstrual cycle. 澶氬洜绱燣ogistic鍥炲綊鍒嗘瀽鏄剧ず:鎵嬫湳鏃堕棿1h(OR=3.176,95%CI 1.567~6.436,P=0.001),PONV鍙，

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