神经阻滞联合干扰电疗法治疗带状疱疹后遗神经痛的临床观察

发布时间：2018-10-13 10:27

【摘要】：目的:本文主要观察并探讨神经阻滞联合干扰电疗法治疗带状疱疹后遗肋间神经痛(postherpetic intercostal neuralgia,PHN)的有效性及安全性。方法:选择我院疼痛门诊收治的PHN患者60例,随机分为A(对照组)、B(治疗组),每组30例。A组行口服普瑞巴林加相应部位的肋间神经阻滞治疗;B组在同样药物的基础上作相应肋间神经阻滞联合干扰电疗法。分别于治疗前、治疗后1周、治疗后8周观察并记录两组患者的视觉模拟评分(VAS)、睡眠质量评分(QS)以及不良反应的发生情况。两组患者的近期和远期疗效可通过两种评分来综合比较。结果:两组患者在性别、年龄、病程、治疗前VAS评分及QS评分等一般资料的比较上,差异无统计学意义(P0.05),具有可比性。与治疗前比较,治疗后1周和治疗后8周两组患者的VAS及QS评分均有所降低,且治疗后1周及治疗后8周B组的VAS及QS评分均明显低于A组,差异有统计学意义(P0.05)。远期(8周后)综合疗效比较中可以得出,两组患者的治疗总有效率均为100%,A组显效率为70%(21/30),B组显效率为93%(28/30)。与B组相比,A组显效率明显降低,差异有统计学意义(χ2=1.92 P0.05)。两组患者不良反应的记录中,A组有3例患者,B组有2例患者肋间神经阻滞后出现头晕症状,休息数分钟后缓解,无感染、呼吸困难、血气胸的发生。两组患者在干扰电治疗中均无皮肤刺激反应和皮肤烧灼等不良反应的发生。结论:神经阻滞联合干扰电疗法能更有效的缓解或解除PHN患者的痛苦,效果更为持久,精神状态也能很好的改善,生活质量也有很大的提高,临床上值得推荐应用。
[Abstract]:Objective: to investigate the efficacy and safety of nerve block combined with interference electrotherapy in the treatment of intercostal neuralgia after herpes zoster. Methods: sixty patients with PHN were selected from pain outpatient department in our hospital. Group A (control group, 30 cases) were randomly divided into two groups: group A (group A) and group B (group B) were given intercostal nerve block combined with intercostal nerve block on the basis of the same drug. Visual analogue score (VAS),) sleep quality score (QS) and adverse reaction (ADR) were observed and recorded before treatment 1 week after treatment and 8 weeks after treatment. The short-term and long-term outcomes of the two groups can be comprehensively compared by two scores. Results: there was no significant difference in sex, age, course of disease, VAS score and QS score between the two groups (P0.05). The scores of VAS and QS in group B were significantly lower than those in group A 1 week after treatment and 8 weeks after treatment, and the scores of VAS and QS in group B were significantly lower than those in group A at 1 week and 8 weeks after treatment (P0.05). The long-term (8 weeks later) comprehensive efficacy comparison showed that the total effective rate of both groups was 70% in group A (93%) in group 21 / 30), B (28 / 30). Compared with group B, the effective rate of group A was significantly lower than that of group B (蠂 2 1.92 P 0.05). There were 3 cases in group A and 2 cases in group B with dizziness after intercostal nerve block. The symptoms were relieved after a few minutes rest, no infection, dyspnea and hemopneumothorax occurred. There were no adverse reactions such as skin irritation and skin cauterization in both groups. Conclusion: nerve block combined with interference therapy can alleviate or relieve the pain of PHN more effectively, the effect is more lasting, the mental state can also be improved, and the quality of life is also greatly improved, which is worthy of clinical recommendation.
【学位授予单位】：蚌埠医学院
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R614

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