甲状腺外科临床数据库的建立及初步应用

发布时间：2018-10-16 16:07

【摘要】：目的1、建立便于甲状腺外科临床研究的数据库系统,利用该系统对临床资料进行保存和查询、分析和总结、交流和共享。2、收集接受经口腔前庭入路腔镜甲状腺切除术患者的临床资料,探讨该术式的临床应用价值。方法1、收集2011年1月至2014年12月期间在暨南大学附属第一医院普外科住院的2164例甲状腺疾病患者的临床资料,将所获资料录入到计算机管理的数据库系统中,按年龄、性别、接受手术方式、疾病种类的不同进行分组,采用SPSS13.0软件进行统计学分析。2、从上述资料库中查询并提取所有在我院接受过经口腔前庭入路腔镜甲状腺切除术患者的临床资料,在安全性、可行性及美容效果方面对该术式进行分析,探讨其临床价值。结果1、2011~2014年间,甲状腺疾病外科住院患者人数呈逐年递增趋势,4年间收治2164人次,男女比例为1:3.87,共实施甲状腺手术1903台。发病年龄集中在30~60岁。结节性甲状腺肿患病人数最多,占总人次的69.6%,各种甲状腺疾病的构成比逐年有波动,甲亢呈递减趋势,甲状腺癌及其后期治疗者呈递增趋势。2、共57例患者接受经口腔前庭入路腔镜甲状腺切除术的治疗,所有患者均成功完成手术,无中转开放,手术时间为107.3分钟(60~205分钟),术中出血量约18毫升(5~30毫升),术后平均住院时间5.2天(3~11天)。术后发热4例,口腔感染2例,颏下皮肤小块瘀斑3例,下颌皮肤裂伤1例,手足麻木4例。无皮下积液感染,无喉上神经、喉返神经及甲状旁腺的永久性损伤。所有患者对美容效果十分满意。结论1、建立的甲状腺疾病外科住院患者临床数据库能为甲状腺外科领域的临床和基础研究提供充足的病历资料参考支持。2、经口腔前庭入路腔镜甲状腺切除术安全可行,美容效果好,有临床应用前景。
[Abstract]:Objective 1. To establish a database system for the clinical study of thyroid surgery, and to use the system to save, query, analyze and summarize the clinical data. The clinical data of patients undergoing endoscopic thyroidectomy via oral vestibular approach were collected and the clinical value of the procedure was discussed. Methods 1. The clinical data of 2164 patients with thyroid diseases in general surgery department of the first affiliated Hospital of Jinan University from January 2011 to December 2014 were collected and recorded into the computerized database system according to age and sex. Results (1) from 2011 to 2014, the number of patients hospitalized in surgery of thyroid diseases was increasing year by year, 2164 patients were admitted in four years, the ratio of male to female was 1: 3.87. A total of 1903 thyroid surgeries were performed. The age of onset was 30 to 60 years old. The number of patients with nodular goiter was the most, accounting for 69.6 of the total. The constituent ratio of various thyroid diseases fluctuated year by year, and the rate of hyperthyroidism decreased. There was an increasing trend of thyroid cancer and its late treatment. 2. A total of 57 patients underwent endoscopic thyroidectomy via oral vestibular approach. The operative time was 107.3 minutes (60 ~ 205min), the blood loss during operation was about 18 ml (5 ~ 30 ml), and the average postoperative hospitalization time was 5.2 days (3 ~ 11 days). There were 4 cases of fever, 2 cases of oral infection, 3 cases of submental skin ecchymosis, 1 case of mandibular skin laceration, 4 cases of numbness of hand and foot. No subcutaneous effusion infection, no permanent damage to the superior laryngeal nerve, recurrent laryngeal nerve and parathyroid gland. All patients were satisfied with the beauty effect. Conclusion 1. The clinical data base of thyroid disease surgery inpatients can provide sufficient reference for the clinical and basic research of thyroid surgery. 2. Endoscopic thyroidectomy via oral vestibule approach is safe and feasible. Good cosmetic effect, clinical application prospects.
【学位授予单位】：暨南大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R653

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