利多卡因注射液联合罗哌卡因注射液对断指再植术的麻醉疗效
发布时间：2018-10-18 11:34
【摘要】：目的观察利多卡因注射液联合罗哌卡因注射液对断指再植术的麻醉疗效与安全性。方法将72例进行断指再植手术患者随机分为对照组36例和试验组36例。对照组予以罗哌卡因注射液10 mL,上肢静脉注射;试验组在对照组治疗的基础上,予以利多卡因注射液10 mL,上肢静脉注射。比较2组患者的麻醉效果、C反应蛋白(CRP)和药物不良反应的发生情况。结果试验组和对照组的麻醉效果Ⅰ级分别为97.22%(35/36例)和83.33%(30/36例),差异有统计学意义(P0.05)。术后1,3 d,试验组的CRP分别为(7.25±1.07),(7.14±0.96)mg·L~(-1),对照组的CRP分别为(8.12±1.18),(7.90±1.01)mg·L~(-1),差异均有统计学意义(均P0.05)。试验组的药物不良反应主要有肢动和皮肤潮红,对照组的药物不良反应主要有肢动、皮肤潮红和皮肤瘙痒。试验组和对照组的药物不良反应发生率分别为5.56%和22.22%,差异有统计学意义(P0.05)。结论利多卡因注射液联合罗哌卡因注射液对断指再植术有较好的麻醉效果,且安全性较高。
[Abstract]:Objective to observe the anesthetic efficacy and safety of lidocaine injection combined with ropivacaine injection for replantation of severed fingers. Methods 72 patients were randomly divided into control group (n = 36) and experimental group (n = 36). The control group was treated with ropivacaine injection for 10 mL, and the experimental group with lidocaine injection for 10 mL,. The anaesthesia effects, C reactive protein (CRP) and adverse drug reactions were compared between the two groups. Results the anesthetic effects of the experimental group and the control group were 97.22% (35 / 36 cases) and 83.33% (30 / 36 cases) respectively. The difference was statistically significant (P0.05). The CRP of the trial group was (7.25 卤1.07), (7.14 卤0.96 mg L ~ (-1) on the 3rd day after operation, and the CRP of the control group was (8.12 卤1.18), (7.90 卤1.01 mg L ~ (-1), the difference was statistically significant (P0.05). The main adverse drug reactions in the test group were limb movement and flushing, while in the control group they were limb movement, flushing and pruritus. The incidence of adverse drug reactions in test group and control group were 5.56% and 22.22% respectively, the difference was statistically significant (P0.05). Conclusion Lidocaine injection combined with ropivacaine injection has better anaesthesia effect on replantation of severed fingers and has higher safety.
【作者单位】： 福建省立医院麻醉科;福建中医药大学附属第二人民医院福建省第二人民医院麻醉科;广州医科大学附属乐从医院麻醉科;
【基金】：佛山市医学类科技攻关基金资助项目(20151021030016)
【分类号】：R614
本文编号：2279003
[Abstract]:Objective to observe the anesthetic efficacy and safety of lidocaine injection combined with ropivacaine injection for replantation of severed fingers. Methods 72 patients were randomly divided into control group (n = 36) and experimental group (n = 36). The control group was treated with ropivacaine injection for 10 mL, and the experimental group with lidocaine injection for 10 mL,. The anaesthesia effects, C reactive protein (CRP) and adverse drug reactions were compared between the two groups. Results the anesthetic effects of the experimental group and the control group were 97.22% (35 / 36 cases) and 83.33% (30 / 36 cases) respectively. The difference was statistically significant (P0.05). The CRP of the trial group was (7.25 卤1.07), (7.14 卤0.96 mg L ~ (-1) on the 3rd day after operation, and the CRP of the control group was (8.12 卤1.18), (7.90 卤1.01 mg L ~ (-1), the difference was statistically significant (P0.05). The main adverse drug reactions in the test group were limb movement and flushing, while in the control group they were limb movement, flushing and pruritus. The incidence of adverse drug reactions in test group and control group were 5.56% and 22.22% respectively, the difference was statistically significant (P0.05). Conclusion Lidocaine injection combined with ropivacaine injection has better anaesthesia effect on replantation of severed fingers and has higher safety.
【作者单位】： 福建省立医院麻醉科;福建中医药大学附属第二人民医院福建省第二人民医院麻醉科;广州医科大学附属乐从医院麻醉科;
【基金】：佛山市医学类科技攻关基金资助项目(20151021030016)
【分类号】：R614
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