椎体压缩性骨折愈合过程中骨痂骨密度变化及其临床意义

发布时间：2018-10-18 16:19

【摘要】：目的观察椎体压缩性骨折骨痂骨密度变化与病程长度的关系,探讨双能X线骨密度仪术前定位陈旧性椎体骨折不愈合的可行性。方法本院2013年1月至2016年1月采用椎体后凸成形术(percutaneous kyphoplasty,PKP)治疗腰1椎体压缩性骨折(均经磁共振成像或SPECT-CT明确诊断)患者66例,年龄60~80岁,均为绝经后女性。按病程长度分为A组(对照组)、B组(新鲜骨折组)、C组(亚急性期骨折组)、D组(陈旧性骨折不愈合组)。运用方差分析观察骨密度比率(腰1椎体骨密度/腰2椎体骨密度×100%)与病程长度的关系。结果各组间年龄、身高、体重差异无统计学意义(P0.05),各组间骨密度比率差异有统计学意义(F=34.839,P0.05),在各组多重比较中,A组与B组间差异无统计学意义(P0.05),其余两组间差异有统计学意义(P0.05)。结论椎体压缩性骨折骨痂骨密度随病程延长而增加,陈旧性骨折不愈合期骨痂骨密度较邻近椎体明显增高,在条件有限的情况下,双能X线骨密度仪不失为术前定位"责任椎"的一种好方法。
[Abstract]:Objective to observe the relationship between bone mineral density (BMD) of callus and course of disease in vertebral compression fracture, and to explore the feasibility of localization of nonunion of old vertebral fracture by dual energy X-ray absorptiometry. Methods from January 2013 to January 2016, 66 cases of lumbar vertebral compression fracture (all diagnosed by magnetic resonance imaging or SPECT-CT) were treated with kyphoplasty (percutaneous kyphoplasty,PKP). All of them were postmenopausal women. According to the duration of the disease, they were divided into group A (control group,), B group) (fresh fracture group,), C group, subacute fracture group,), D group (old fracture non-union group). The relationship between bone mineral density ratio (lumbar 1 vertebra bone density / lumbar 2 vertebral bone density 脳 100%) and duration of disease was observed by variance analysis. Results there was no significant difference in age, height and weight among the groups (P0.05), but there was a significant difference in BMD ratio between each group (P 0.05). There was no significant difference between group A and group B (P0.05), but there was no significant difference between group A and group B (P0.05). Conclusion the bone mineral density of callus of vertebral compression fracture increases with the prolongation of the course of disease. The bone mineral density of callus in the old fracture is higher than that in the adjacent vertebral body, and the condition is limited. Dual-energy X-ray absorptiometry is a good method to locate responsibility vertebrae before operation.
【作者单位】：南京医科大学附属南京医院;
【基金】：南京市医学科技发展重点项目(ZKX14032)
【分类号】：R580;R683

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