改良纤维蛋白脂肪复合物治疗瘢痕性凹陷的临床观察

发布时间：2018-10-21 19:59

【摘要】：目的:探讨应用改良自体纯化脂肪颗粒复合富血小板纤维蛋白(platelet-rich fibrin,PRF)注射移植对面部瘢痕性凹陷畸形进行修复的手术方法。方法:对27例面部凹陷畸形患者,取自体脂肪经离心纯化,复合PRF,瘢痕粘连松解,局部注射填充。结果:患者术后局部畸形矫正满意,术区几乎无新增瘢痕,并且原有瘢痕质地有一定程度改善,脂肪供区无并发症发生。27例均获随访,随访时间6个月至2年,效果满意,无局部硬结、感染、脂肪液化。结论:应用改良富血小板纤维蛋白复合自体脂肪,能有效提高脂肪的成活率,减少移植后液化、坏死,是修复面部瘢痕性凹陷畸形的有效方法,在临床值得推广。
[Abstract]:Objective: to investigate the method of modified autogenous purified fat granules combined with platelet-rich fibrin (platelet-rich fibrin,PRF) injection for the repair of facial scarring deformity. Methods: autogenous fat was extracted from 27 patients with facial depression and purified by centrifugation, combined with PRF, scar adhesion release and local injection filling. Results: the correction of local deformity was satisfactory, there was almost no new scar in the operation area, and the texture of the original scar was improved to some extent, and no complications occurred in the fat donor area. All the 27 cases were followed up for 6 months to 2 years, and the results were satisfactory. No local sclerosis, infection, fat liquefaction. Conclusion: the application of modified platelet-rich fibrin combined with autologous fat can effectively increase the survival rate of fat, reduce liquefaction and necrosis after transplantation, and is an effective method for repairing facial scarring deformity, which is worth popularizing in clinic.
【作者单位】：南华大学附属第一医院医疗美容科;中南大学湘雅附三医院烧伤整形科;上海交通大学医学院附属第九人民医院整复外科;
【基金】：湖南省自然科学基金资助项目(编号:2015JJ6100)
【分类号】：R622

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