乳腺手术后局部组织感染的革兰阳性菌特征及耐药性研究

发布时间：2018-10-30 16:50

【摘要】：目的分析引起乳腺手术后局部组织感染的革兰阳性菌特征及药敏试验结果,为乳腺手术后局部组织感染的治疗提供参考。方法选取2012年1月-2016年10月于医院行乳腺手术治疗术后发生局部组织感染的120例患者临床资料,患者在术后有局部组织感染迹象时采集局部分泌物,行细菌培养及药敏试验。结果 120例患者其中86例培养出革兰阳性菌,阳性率为71.67%,革兰阳性菌共97株,以葡萄球菌属为主,共75株占77.32%;葡萄球菌属对阿莫西林/克拉维酸、氨苄西林/舒巴坦、头孢哌酮、万古霉素耐药率均50.00%,对环丙沙星、红霉素、庆大霉素、左氧氟沙星、呋喃妥因、苯唑西林钠、青霉素、四环素耐药率50.00%。结论引起乳腺手术后局部组织感染的革兰阳性菌以葡萄球菌属为主,其次为肠球菌属,以单一病原菌感染多见,葡萄球菌属和肠球菌属对阿莫西林/克拉维酸、氨苄西林/舒巴坦、头孢哌酮和万古霉素等抗菌药物耐药率低,对其他临床常用的抗菌药物耐药性严重。
[Abstract]:Objective to analyze the characteristics of Gram-positive bacteria and the results of drug sensitivity test in local tissue infection after breast surgery, and to provide a reference for the treatment of local tissue infection after breast surgery. Methods from January 2012 to October 2016, 120 patients with local tissue infection were treated by breast surgery in hospital from January 2012 to October 2016. Local secretions were collected and bacterial culture and drug sensitivity tests were performed when the patients showed signs of local tissue infection. Results the positive rate of Gram-positive bacteria was 71.67 in 86 cases of 120 patients, 97 strains of Gram-positive bacteria were found, and 75 strains were staphylococci (77.32%). Staphylococcus was resistant to amoxicillin / clavulanic acid, ampicillin / sulbactam, cefoperazone and vancomycin, and was resistant to ciprofloxacin, erythromycin, gentamycin, levofloxacin, furantoin, oxacillin sodium. Penicillin, tetracycline resistance rate was 50.00g. Conclusion the Gram-positive bacteria causing local tissue infection after mammary gland operation are mainly Staphylococcus, followed by Enterococcus, and most of them are single pathogen. Staphylococcus and Enterococcus are resistant to amoxicillin / clavulanic acid. Ampicillin / sulbactam, cefoperazone and vancomycin have low antimicrobial resistance and severe resistance to other commonly used antibiotics.
【作者单位】：焦作煤业(集团)有限责任公司中央医院普外二科;
【分类号】：R655.8

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