疝气日间手术中盐酸羟考酮与腹横肌平面神经阻滞联合应用的适宜剂量

发布时间：2018-11-06 18:54

【摘要】：目的探讨盐酸羟考酮用于疝气日间手术的适宜剂量。方法将60例择期行疝气日间手术患者随机均分为0.1 mg/kg组、0.15 mg/kg组、0.2 mg/kg组,各组分别静推盐酸羟考酮注射液0.1、0.15、0.2 mg/kg,然后行腹横肌平面神经阻滞,麻醉完全后常规行疝气日间手术。三组分别于术前(t0)、切皮时(t1)、探查疝囊时(t2)、缝皮时(t3)、手术结束时(t4)行Wong-baker面部表情量表评分、Ramsay镇静评分。比较三组补救镇痛率、镇痛满意度评分及术后不良反应发生率。结果 0.15 mg/kg组、0.2 mg/kg组t2、t3、t4时Wong-baker面部表情量表评分均低于0.1 mg/kg组(P均0.05)。0.15 mg/kg组、0.2 mg/kg组t1、t2、t3时Ramsay镇静评分均高于0.1 mg/kg组同期,但0.2 mg/kg组升高更明显(P均0.05)。0.15 mg/kg组、0.2 mg/kg组补救镇痛率均低于0.1 mg/kg组,镇痛满意度评分均高于0.1 mg/kg组(P均0.05)。0.2 mg/kg组不良反应发生率均高于0.1 mg/kg组、0.15 mg/kg组(P均0.05)。结论疝气日间手术中应用0.15 mg/kg盐酸羟考酮联合腹横肌平面阻滞的镇痛、镇静效果较好,安全性较高。
[Abstract]:Objective to study the appropriate dosage of hydroxycodone hydrochloride for hernia day operation. Methods 60 patients undergoing selective hernia operation were randomly divided into 0. 1 mg/kg group, 0. 15 mg/kg group and 0. 2 mg/kg group. Then the abdominal transverse nerve block was performed, and the hernia operation was performed after complete anesthesia. Wong-baker facial expression scale and Ramsay sedation score were performed in the three groups before operation (t 0), incision (t 1), exploration of hernia sac (t 2), suture skin (t 3) and end of operation (t 4). The rescue analgesia rate, analgesic satisfaction score and incidence of postoperative adverse reactions were compared among the three groups. Results the scores of Wong-baker facial expression scale in 0. 15 mg/kg group, 0. 2 mg/kg group and 0. 2 mg/kg group were lower than that in 0. 1 mg/kg group (P 0. 05). The Wong-baker scores in 0. 15 mg/kg group and 0. 2 mg/kg group were significantly lower than those in 0. 1 mg/kg group and 0. 2 mg/kg group, respectively. At t _ 3, Ramsay sedation score was higher than that in 0.1 mg/kg group, but increased significantly in 0.2 mg/kg group (P 0.05). The rescue analgesia rate in 0.2 mg/kg group was lower than that in 0.1 mg/kg group. The scores of analgesic satisfaction were higher than that of 0. 1 mg/kg group (P 0. 05), the incidence of adverse reactions in 0. 2 mg/kg group was higher than that in 0. 1 mg/kg group and 0. 15 mg/kg group (P 0. 05). Conclusion the analgesic effect of 0.15 mg/kg hydroxycodone hydrochloride combined with abdominal transverse muscle block in hernia operation is better and the safety is higher.
【作者单位】：山东中医药大学;山东中医药大学附属医院;
【分类号】：R614

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