短肽型肠内营养制剂对脊柱术后患者早期营养支持的耐受性及效果观察

发布时间：2018-11-15 16:21

【摘要】：目的探讨脊柱术后患者对两种肠内营养制剂的耐受性,观察肠道功能恢复情况,评价营养支持效果。方法选取2015年3-5月第三军医大学新桥医院骨科脊柱术后患者100例,分为研究组50例,对照组50例。研究组给予短肽型肠内营养制剂支持,对照组给予整蛋白型肠内营养制剂支持,比较两组患者血清总蛋白、白蛋白、前白蛋白、术后首次肛门排气时间、术后24 h内肠鸣音情况及术后24 h内腹胀、腹泻、恶心、呕吐发生率。结果与对照组比较,研究组首次肛门排气时间显著缩短[(14.4±5.1)vs(16.8±5.0)h,P=0.021];研究组腹胀发生率、恶心发生率显著低于对照组(4%vs18%,P=0.025;6%vs 24%,P=0.012);营养支持前、后,患者血清总蛋白、白蛋白、前白蛋白研究组与对照组比较差异无统计学意义(P0.05)。结论短肽型肠内营养制剂能显著缩短脊柱术后患者胃肠道恢复时间并提高患者胃肠道耐受性。
[Abstract]:Objective to investigate the tolerance of two enteral nutrition preparations after spinal operation, observe the recovery of intestinal function and evaluate the effect of nutritional support. Methods 100 cases of orthopedic spine operation in Xinqiao Hospital of third military Medical University from May to May 2015 were selected and divided into study group (50 cases) and control group (50 cases). The study group was given short peptide enteral nutrition preparation, while the control group was given integral protein enteral nutrition preparation support. The serum total protein, albumin, prealbumin and the first anal exhaust time after operation were compared between the two groups. The incidence of abdominal distension, diarrhea, nausea and vomiting within 24 hours after operation. Results compared with the control group, the first anal exhaust time in the study group was significantly shortened [(14.4 卤5.1) vs (, 16.8 卤5.0) hp, 0.021]. The incidence of abdominal distension and nausea in the study group was significantly lower than that in the control group (4% vs 0.025% vs 24% P0. 012). Before and after nutritional support, there was no significant difference in serum total protein, albumin and prealbumin between the study group and the control group (P0.05). Conclusion short peptide enteral nutrition can shorten the recovery time of gastrointestinal tract and improve the tolerance of gastrointestinal tract after spinal surgery.
【作者单位】：第三军医大学新桥医院营养科;第三军医大学新桥医院骨科;
【基金】：重庆市科技攻关项目(CSTC2015shmszx120014)~~
【分类号】：R459.3;R687.3

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