高血压脑出血术后应用镇痛药（盐酸丙帕他莫）对病情的影响
发布时间：2018-11-15 22:18
【摘要】：目的:探索高血压脑出血术后患者接受镇痛治疗对血压、意识状态、术后再出血发生率的影响,探讨高血压脑出血术后患者镇痛治疗与控制血压、防治术后再出血的应用区间及治疗策略。方法:选取2011年8月至2014年6月在山西医科大学第一医院急诊科因高血压脑出血收住院并行颞部开颅脑内血肿清除术患者共50例,据其药物特性,记录应用盐酸丙帕他莫镇痛治疗(实验组)与常规治疗(对照组)患者之间不同时间点血压、意识状态、有无术后再出血等临床指标,采用SPSS17.0软件进行计数资料独立样本t检验及计量资料卡方检验,分析所得结果。结果:昏迷组患者术后应用盐酸丙帕他莫1h平均动脉压与常规治疗组平均动脉压进行独立样本t检验,p值0.05,差异有统计学意义,余时间点p值0.05,无统计学意义;清醒-嗜睡组、朦胧组各时间点平均动脉压经独立样本t检验,p值0.05,无统计学意义;实验组与对照组镇痛与烦躁的发生率经卡方检验p值0.05,差异有统计学意义;实验组与对照组镇痛与术后再出血的发生率经卡方检验p值0.05,无统计学意义。结论:高血压脑出血术后昏迷的患者应用盐酸丙帕他莫镇痛对降低血压、减小血压波动幅度有积极作用;应用盐酸丙帕他莫可以减少高血压脑出血术后患者烦躁的发生。
[Abstract]:Objective: to explore the effect of analgesic therapy on blood pressure, consciousness and the incidence of postoperative rebleeding in patients with hypertensive intracerebral hemorrhage after operation, and to explore the analgesic treatment and control of blood pressure in patients with hypertensive intracerebral hemorrhage. Application interval and treatment strategy for prevention and treatment of postoperative rebleeding. Methods: from August 2011 to June 2014, 50 patients with hypertensive intracerebral hemorrhage were selected from the Emergency Department of the first Hospital of Shanxi Medical University and treated with craniotomy for intracerebral hematoma clearance. Blood pressure, state of consciousness, postoperative bleeding and so on were recorded at different time points between patients treated with propatamol hydrochloride (experimental group) and routine therapy (control group). SPSS17.0 software was used to carry out t-test and chi-square test of counting data, and the results were analyzed. Results: the patients in coma group were treated with propanamol hydrochloride for 1 h mean arterial pressure after operation, and the average arterial pressure in routine treatment group was tested by t test (p = 0.05), the difference was statistically significant, and the remaining time point (p = 0.05) was not statistically significant. There was no significant difference in the mean arterial pressure between awake and sleepiness group and hazy group by t test of independent sample (p = 0.05), the incidence of analgesia and irritability in experimental group and control group was significantly higher than that in control group (p = 0.05). The incidence of analgesia and postoperative rebleeding in experimental group and control group was 0.05 by chi-square test (p = 0.05). Conclusion: propatamol hydrochloride has a positive effect on lowering blood pressure and reducing the fluctuation of blood pressure in patients with coma after hypertensive intracerebral hemorrhage and can reduce the occurrence of irritability in patients with hypertensive intracerebral hemorrhage after operation.
【学位授予单位】：山西医科大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R651.1
本文编号：2334560
[Abstract]:Objective: to explore the effect of analgesic therapy on blood pressure, consciousness and the incidence of postoperative rebleeding in patients with hypertensive intracerebral hemorrhage after operation, and to explore the analgesic treatment and control of blood pressure in patients with hypertensive intracerebral hemorrhage. Application interval and treatment strategy for prevention and treatment of postoperative rebleeding. Methods: from August 2011 to June 2014, 50 patients with hypertensive intracerebral hemorrhage were selected from the Emergency Department of the first Hospital of Shanxi Medical University and treated with craniotomy for intracerebral hematoma clearance. Blood pressure, state of consciousness, postoperative bleeding and so on were recorded at different time points between patients treated with propatamol hydrochloride (experimental group) and routine therapy (control group). SPSS17.0 software was used to carry out t-test and chi-square test of counting data, and the results were analyzed. Results: the patients in coma group were treated with propanamol hydrochloride for 1 h mean arterial pressure after operation, and the average arterial pressure in routine treatment group was tested by t test (p = 0.05), the difference was statistically significant, and the remaining time point (p = 0.05) was not statistically significant. There was no significant difference in the mean arterial pressure between awake and sleepiness group and hazy group by t test of independent sample (p = 0.05), the incidence of analgesia and irritability in experimental group and control group was significantly higher than that in control group (p = 0.05). The incidence of analgesia and postoperative rebleeding in experimental group and control group was 0.05 by chi-square test (p = 0.05). Conclusion: propatamol hydrochloride has a positive effect on lowering blood pressure and reducing the fluctuation of blood pressure in patients with coma after hypertensive intracerebral hemorrhage and can reduce the occurrence of irritability in patients with hypertensive intracerebral hemorrhage after operation.
【学位授予单位】：山西医科大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R651.1
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