苦柏颗粒洗剂对湿热下注型低位单纯性肛瘘术后愈合的临床观察

发布时间：2018-11-20 11:54

【摘要】：目的:观察苦柏颗粒洗剂对湿热下注型低位单纯性肛瘘术后愈合的临床疗效,为其临床推广应用提供理论依据。方法:将符合诊断标准采用低位单纯性肛瘘切除术的60例患者随机分为两组,治疗组和对照组各30例。进行21天疗程对比治疗,其中治疗组以苦柏颗粒洗剂治疗,对照组以痔疾洗液治疗。在治疗结束后进行临床疗效评价,比较前后两组的患者创面疼痛、渗液情况及创面肉芽组织生长情况,并做出评分,然后应用spss17.0系统软件进行统计学分析。结果:选定病例后,在两组对比治疗前,对患者的年龄、性别、病程、术后创面情况、疼痛、创面分泌物及创面肉芽组织生长情况等进行比较,差异均无统计学意义,具有可比性。研究结果分析如下:(1)疼痛评分比较:两组术后第3天和第7天患者创面疼痛状况有统计学意义(P0.05),治疗组评分优于对照组。第14天和第21天疼痛状况无明显差异,无统计学意义(P0.05)。(2)创面分泌物:两组术后第3天、第7天检查创面所敷纱布情况并记录沾染纱布层数,进行分泌物比较,差别均有统计学意义(P0.05),治疗组创面分泌物评分优于对照组。术后第14天、第21天,观察组创面分泌物计分比较,P0.05,差异无统计学意义。(3)创面肉芽组织生长情况:治疗后第7天评分比较,两组差异无统计学意义(P0.05)。治疗后第14天、第21天评分比较两组差异均具有统计学意义(P0.05),两组相比较治疗组优于对照组。(4)总疗效和创面愈合时间:两组患者治疗后均痊愈,治疗组平均创面愈合时间为19.13±2.63天;对照组平均创面愈合时间为20.27±2.38天。结果:两组平均创面愈时间比较差异有统计学意义(P0.05),治疗组明显优于对照组。结论:苦柏颗粒洗剂可以显著减轻湿热下注型低位单纯性肛瘘患者术后创面的疼痛,减少创面渗出,促进创面肉芽组织生长,加快创面愈合。
[Abstract]:Objective: to observe the clinical effect of Kubai granule lotion on the healing of low grade anal fistula with damp-heat injection, and to provide theoretical basis for its clinical application. Methods: 60 patients with low simple anal fistula were randomly divided into two groups: treatment group (n = 30) and control group (n = 30). The treatment group was treated with Kubai granule lotion and the control group was treated with hemorrhoid lotion. At the end of the treatment, the clinical efficacy was evaluated, and the wound pain, exudation and granulation tissue growth were compared before and after the treatment. Then the spss17.0 system software was used for statistical analysis. Results: there was no significant difference in age, sex, course of disease, postoperative wound condition, pain, wound secretion and granulation tissue growth between the two groups. Comparable. The results of the study were as follows: (1) comparison of pain scores: the pain status of the patients in the treatment group was significantly higher than that in the control group on the 3rd and 7th day after operation (P0.05). There was no significant difference in pain status between day 14 and day 21 (P0.05). (2): on the 3rd and 7th day after operation, the wound gauze was examined and the number of coated gauze layers was recorded, and the secretion was compared between the two groups. The difference was statistically significant (P0.05). The score of wound secretion in the treatment group was better than that in the control group. On the 14th and 21st day after operation, the score of wound secretion in the observation group was not statistically significant (P 0.05). (3) the granulation tissue growth of the wound: the score was not significantly different between the two groups on the 7th day after treatment (P0.05). On the 14th day and 21st day after treatment, the scores of the two groups were significantly different (P0.05). The treatment group was better than the control group. (4) the total curative effect and wound healing time: the two groups were cured after treatment. The average wound healing time in the treatment group was 19.13 卤2.63 days. The average wound healing time in the control group was 20.27 卤2.38 days. Results: the average wound healing time of the two groups was significantly different (P0.05), the treatment group was significantly better than the control group. Conclusion: Kubai granule lotion can significantly reduce the pain of the wound, reduce the exudation of the wound, promote the growth of granulation tissue and accelerate the wound healing.
【学位授予单位】：黑龙江省中医药科学院
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R657.16

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