烧伤创面病原菌感染的相关因素分析

发布时间：2018-11-27 15:27

【摘要】：目的探讨引起烧伤创面病原菌感染发生的相关因素及病原菌分布状况,为烧伤感染的预防及治疗提供参考。方法收集2012年1月-2015年12月在医院诊治的212例烧伤患者临床资料,回顾性分析创面病原菌培养结果及引起感染的相关因素。结果 212例患者发生创面感染者164例,感染率为77.36%;创面分泌物中培养出185株病原菌,其中革兰阴性菌131株占70.81%,革兰阳性菌49株占26.49%,真菌5株占2.70%,感染病原菌以铜绿假单胞菌、鲍曼复合醋酸钙不动杆菌、金黄色葡萄球菌为主,分别占18.38%、15.14%、11.89%;单因素及多因素logistic回归分析显示,烧伤面积越大、烧伤程度越深、预防使用抗菌药物种类越多感染率越高(P0.05),入院后预防使用抗菌药物、合并休克、平时有自购抗菌药物滥用习惯、有长期服用糖皮质激素治疗疾病史等因素时感染率高(P0.05)。结论烧伤发生后创面感染率极高,感染病原菌主要是革兰阴性菌,引起烧伤感染的因素较多,应针对性的进行干预以降低感染发生。
[Abstract]:Objective to investigate the related factors and distribution of pathogenic bacteria in burn wound, and to provide reference for the prevention and treatment of burn infection. Methods the clinical data of 212 burn patients were collected from January 2012 to December 2015. The culturing results of pathogenic bacteria and the related factors of infection were analyzed retrospectively. Results 164 cases of wound infection occurred in 212 patients, the infection rate was 77.36; 185 strains of pathogenic bacteria were cultured in wound secretion, of which 131 strains were Gram-negative bacteria (70.81strains), 49 Gram-positive bacteria (49 strains) and 5 fungi strains (2.70%). The pathogens were infected by Pseudomonas aeruginosa. Baumann compound Acinetobacter calcium Acinetobacter, Staphylococcus aureus, accounted for 18.38% 15.14% 11.89%; Univariate and multivariate logistic regression analysis showed that the larger the burn area, the deeper the burn degree, the higher the infection rate of prophylactic use of antimicrobial agents (P0.05). Usually have the habit of self-purchase antimicrobial abuse, long-term use of glucocorticoid treatment of disease history and other factors when the infection rate was high (P0.05). Conclusion the infection rate of burn wound is very high, the main pathogenic bacteria are Gram-negative bacteria, there are many factors causing burn infection, so intervention should be carried out in order to reduce the incidence of infection.
【作者单位】：唐山市工人医院烧伤整形二科监护室;唐山市工人医院烧伤整形二科;
【基金】：河北省医学科学研究重点课题(20150049)
【分类号】：R644

【相似文献】