可吸收形状记忆聚氨酯腰椎间融合器的生物力学评价
[Abstract]:Aim: to evaluate the biomechanical characteristics of an absorbable shape memory polyurethane (shape memory polyurethane,SMPU) lumbar interbody fusion cage (cage) in single segment of cadaveric lumbar spine. Methods: fifteen lumbosacral vertebrae (L1?S1) specimens were randomly divided into 3 groups: autogenous iliac bone group (n = 5) (n = 5), polyether ether ketone (polyetheretherketone,PEEK) group (n = 5) cage group (n = 5). Three kinds of implants were implanted into the lumbar disc nucleus pulposus by lateral approach of lumbar vertebrae. The range of motion (range of motion,ROM) and the axial damage load of each group were measured by mechanical testing machine before and after operation. Results: the results of ROM showed that there was no significant difference in ROM between, SMPU cage group and PEEK cage group in 6 directions: anterior flexion, extension, left bend, right bend, left rotation and right rotation (P0.05). The postoperative ROM in the autogenous iliac bone group was significantly higher than that in the preoperative group (P0.05). The postoperative ROM in the); SMPU cage group was significantly lower than that in the pre-operation group (P0.05). The postoperative ROM of PEEK cage group in 6 directions was significantly lower than that of preoperative group (P0.05). The ROM of). SMPU cage group and PEEK cage group were significantly lower than that of autogenous iliac bone group (P0.05). There was no significant difference in ROM in 6 directions between SMPU cage group and PEEK cage group (P0.05). The results of axial compression test showed that the damage load of: PEEK cage group was significantly higher than that of SMPU cage group and autogenous iliac bone group (P0. 000), SMPU cage group was significantly higher than that of autologous iliac bone group (P0. 000). Conclusion: shape memory polyurethane interbody fusion cage can satisfy the initial stability of lumbar interbody fusion and can bear the physiological load of lumbar vertebrae.
【学位授予单位】:重庆医科大学
【学位级别】:硕士
【学位授予年份】:2017
【分类号】:R687
【参考文献】
相关期刊论文 前10条
1 刘显宏;欧云生;蒋电明;权正学;张乐;陈鑫;胡侦明;;n-HA/PA66与PEEK cage在颈前路椎间盘切除减压术后椎间隙重建的比较研究[J];中国临床解剖学杂志;2012年06期
2 杨曦;宋跃明;孔清泉;龚全;裴福兴;屠重棋;;纳米羟基磷灰石/聚酰胺66椎间融合器植骨融合治疗下腰椎退变性疾病的近期疗效[J];中国修复重建外科杂志;2012年12期
3 张晓彦;罗彦凤;阮长顺;王品品;窦庶华;王远亮;;哌嗪扩链的形状记忆医用材料聚氨酯脲的合成与表征[J];功能材料;2012年08期
4 刘曼;孟耀;周立伟;莫安春;李小玉;李吉东;;纳米羟基磷灰石/聚酰胺66复合膜的结构及与成骨样细胞相容性研究[J];现代口腔医学杂志;2012年01期
5 陈日高;屠重琪;裴福兴;段宏;刘立岷;宋跃明;;纳米羟基磷灰石/聚酰胺66复合物椎间融合器在山羊颈椎融合中的应用[J];中国脊柱脊髓杂志;2010年04期
6 宋跃明;陈日高;刘立岷;龚全;李涛;曾建成;刘浩;裴福兴;屠重琪;段宏;;多孔纳米羟基磷灰石-聚酰胺66椎间融合器治疗胸腰椎爆裂骨折的早期临床研究[J];中华骨科杂志;2010年04期
7 颜泽萱;罗彦凤;黄美娜;王远亮;;拉伸-复形过程对骨修复形状记忆聚氨酯材料细胞相容性的影响[J];中国组织工程研究与临床康复;2010年03期
8 李鸿;李玉宝;严永刚;周刚;王明波;程琳;;纳米羟基磷灰石/聚酰胺66多孔材料制备和生物安全性初步评价[J];生物医学工程学杂志;2008年05期
9 李开南;刘建峰;汪学军;兰海;何智勇;熊成东;张明梅;;可生物降解聚-DL-乳酸腰椎间融合器的设计及生物力学研究[J];中国脊柱脊髓杂志;2007年01期
10 郝勇;周跃;滕海军;曹国勇;潘勇;;聚内消旋乳酸(PDLLA)椎间融合器在椎间降解情况的实验观察[J];中国矫形外科杂志;2006年03期
,本文编号:2374848
本文链接:https://www.wllwen.com/yixuelunwen/waikelunwen/2374848.html