低频脉冲电磁场促进骨愈合的Meta分析

发布时间：2018-12-29 15:21

【摘要】：背景:临床研究证实了低频脉冲电磁场除了用于骨折延迟愈合与骨不连外,对新鲜骨折、骨切除术及疲劳骨折的治疗也有显著疗效。目的:系统评价低频脉冲电磁场促进骨愈合的临床疗效和安全性。方法:通过检索中国学术期刊全文数据库(CNKI)、美国国立医学图书馆生物医学信息检索系统(Pub Med)等数据库中1985年1月至2016年5月有关低频脉冲电磁场促进骨折愈合的随机对照临床研究文献,对纳入文献进行资料提取、方法学质量评价,并采用Rev Man5.1软件进行统计分析。结果与结论:(1)有13篇文献符合纳入标准,共有1 244例患者,均为随机对照临床试验;(2)Meta分析结果显示:低频脉冲电磁场治疗组的总体有效率高于对照组的总体有效率;治疗组的骨折愈合时间显著低于对照组的骨折愈合时间;治疗组的骨密度显著高于对照组的骨密度;(3)结果说明,低频脉冲电磁场促进骨折愈合的总有效率较高,能显著缩短骨折愈合时间且安全性较高,但还需要大量Jadad法评分高的多中心、大样本量随机对照临床试验来进一步验证。
[Abstract]:Background: clinical studies have confirmed that low frequency pulsed electromagnetic fields not only for delayed fracture healing and bone nonunion, but also for fresh fracture, bone resection and fatigue fracture treatment. Objective: to evaluate the clinical efficacy and safety of low-frequency pulsed electromagnetic field in bone healing. Methods: by searching the full text database of Chinese academic journals, (CNKI), From January 1985 to May 2016, a randomized controlled clinical study of low-frequency pulsed electromagnetic fields promoting fracture healing was carried out in the biomedical information retrieval system (Pub Med) of the National Library of Medicine of the United States of America. The quality of methodology was evaluated, and Rev Man5.1 software was used for statistical analysis. Results and conclusion: (1) there were 13 articles in accordance with the inclusion criteria, a total of 1 244 patients, all were randomized controlled clinical trials; (2) Meta analysis showed that the total effective rate of the treatment group was higher than that of the control group, and the fracture healing time of the treatment group was significantly lower than that of the control group. The BMD in the treatment group was significantly higher than that in the control group. (3) the results show that the total effective rate of low frequency pulse electromagnetic field in promoting fracture healing is higher, the time of fracture healing is significantly shortened and the safety is higher, but a large number of multi-centers with high Jadad score are needed. Large sample size was further verified by randomized controlled clinical trials.
【作者单位】：乐山师范学院体育学院;陕西师范大学体育学院;
【基金】：陕西师范大学研究生培养创新基金(2015CXS020)~~
【分类号】：R683

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