早期乳腺癌保乳术后3DCRT和eComp放疗技术的剂量学对比研究

发布时间：2019-03-15 13:06

【摘要】：目的:比较早期乳腺癌保乳术后采用三维适形放射治疗(three-dimensional conformal radiotherapy,3DCRT)和电子组织补偿(electronic tissuecompensation,eComp)两种不同放疗方案的剂量学差异。方法:60例早期乳腺癌保乳术后放疗患者,在专用软件上分别设计3DCRT和eComp 2种方案并比较设计方案所耗费时间、辐射剂量机器监测单位(monitor unit,MU)、肿瘤靶区剂量覆盖和正常组织器官受照射剂量等参数之间的差异。结果:设计放疗方案所耗费时间,eComp约比3DCRT多10 min,差异有统计学意义(P=0.000)。3DCRT和eComp的平均MU分别为(300±12)、(302±11)MU(P=0.059)。2种方案都能满足肿瘤靶区的剂量覆盖标准;采用eComp方案,肺、心脏和皮肤剂量更低(P0.05)。结论:在保证肿瘤靶区得到足量照射的前提下,eComp技术可以降低肺、心脏和皮肤的受照射剂量。
[Abstract]:Aim: to compare the dosimetric differences between three-dimensional conformal radiotherapy (three-dimensional conformal radiotherapy,3DCRT) and electronic tissue compensation (electronic tissuecompensation,eComp) after breast-conserving surgery for early breast cancer. Methods: 60 patients with early breast cancer treated by post-breast-conserving radiotherapy were divided into two groups: 3DCRT and eComp, and the time-consuming time of the design was compared. The radiation dose monitoring unit (monitor unit,MU) was designed on the special software. The difference between tumor target dose coverage and irradiation dose of normal tissues and organs. Results: the eComp was about 10 min, longer than that of 3DCRT (P < 0.001), and the average MU of 3DCRT and eComp was (300 卤12), respectively. (302 卤11) MU (P < 0.059). Both of the two schemes could meet the dose coverage criteria of tumor target area. Using eComp regimen, lung, heart and skin doses were lower (P0.05). Conclusion: eComp can reduce the radiation dose of lung, heart and skin on the premise of sufficient dose of radiation to tumor target area. [WT5 "HZ] conclusion: [WT5" BZ] [WT5 "BZ]
【作者单位】： 重庆医科大学附属第一医院肿瘤科;
【基金】：重庆市卫计委医学科研计划资助项目(编号:2015MSXM012)
【分类号】：R737.9
，

本文编号：2440647