开颅手术患者术后炎症因子水平变化预测颅内感染的临床价值
发布时间：2019-05-14 08:36
【摘要】：目的探讨开颅手术术后炎症因子水平变化预测颅内感染的价值。方法回顾性分析2012年1月至2015年1月收治的48例开颅手术患者,术后经脑脊液等辅助检查证实为颅内感染的作为研究组,选取同时期开颅手术无颅内感染患者48例作为对照组,两组均抽取静脉血,观察炎症指标变化情况。结果术后第1天两组白细胞(WBC)、白细胞介素(IL)-6、肿瘤坏死因子(TNF)-α、人S-100b蛋白(S-100b)、C反应蛋白(CRP)、降钙素原(PCT)比较差异无统计学意义(均P0.05),而术后第3天开始研究组WBC、IL-6、TNF-α、S-100b、CRP、PCT水平显著高于对照组,术后第7、14天两组差异越来越大(均P0.05);经颅内感染受试者工作特征(ROC)曲线分析,WBC、IL-6、TNF-α、S-100b、CRP、PCT对颅内感染差异有统计学意义(P0.05)。结论开颅手术后3 d WBC、IL-6、TNF-α、S-100b、CRP、PCT水平无下降则预示患者术后颅内感染可能性大。
[Abstract]:Objective to evaluate the value of inflammatory factors in predicting intracranial infection after craniotomy. Methods from January 2012 to January 2015, 48 patients undergoing craniotomy were analyzed retrospectively. the patients with intracranial infection confirmed by cerebrospinal fluid and other auxiliary examination were used as the study group, and 48 patients without intracranial infection during the same period were selected as the control group. Venous blood was taken from both groups to observe the changes of inflammatory indexes. Results on the first day after operation, (WBC), (IL)-6, tumor necrosis factor (TNF)-伪 and human S 鈮，
本文编号：2476563
[Abstract]:Objective to evaluate the value of inflammatory factors in predicting intracranial infection after craniotomy. Methods from January 2012 to January 2015, 48 patients undergoing craniotomy were analyzed retrospectively. the patients with intracranial infection confirmed by cerebrospinal fluid and other auxiliary examination were used as the study group, and 48 patients without intracranial infection during the same period were selected as the control group. Venous blood was taken from both groups to observe the changes of inflammatory indexes. Results on the first day after operation, (WBC), (IL)-6, tumor necrosis factor (TNF)-伪 and human S 鈮，
本文编号：2476563
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