夏枯草口服液联合头孢地尼分散片治疗慢性乳腺炎的临床效果观察

发布时间：2019-05-15 18:58

【摘要】：目的:观察夏枯草口服液联合抗生素治疗慢性乳腺炎的临床效果。方法:纳入郑州人民医院乳腺外科在2012年1月~2015年5月收治的74例慢性乳腺炎女性患者为资料进行研究。抽签法将其分为2组,每组37例。对照组采用抗生素治疗,观察组在对照组基础上加服夏枯草口服液。将治疗后治疗疗效、治疗前后炎症水平、VAS评分和肿块最大直径以及一年内复发率进行对比分析。结果:观察组总有效率为94.59%,明显高于对照组75.68%。治疗后,观察组血清C反应蛋白(CRP)和肿瘤坏死因子-ɑ(TNF-ɑ)水平分别为(17.11±2.82mg/L、2.03±0.46μg/L),均明显低于对照组(25.27±3.10mg/L、3.24±0.53μg/L)。治疗后,观察组VAS评分和肿块最大直径分别为(1.09±0.26分、1.86±0.21cm),均明显低于对照组(2.21±0.30分、3.06±0.24cm)。(4)观察组24例治愈患者中一年内复发率为8.33%,明显低于对照组19例治愈患者中的复发率36.84%。结论:加服夏枯草口服液可提高治疗疗效,降低炎症、减轻患者疼痛,并降低复发率。
[Abstract]:Objective: to observe the clinical effect of Prunella vulgaris oral liquid combined with antibiotics in the treatment of chronic mastitis. Methods: 74 female patients with chronic mastitis were enrolled in the breast surgery department of Zhengzhou people's Hospital from January 2012 to May 2015. The patients were divided into two groups by drawing lots, 37 cases in each group. The control group was treated with antibiotics, and the observation group was treated with Prunella vulgaris oral liquid on the basis of the control group. The curative effect, inflammatory level before and after treatment, VAS score, maximum diameter of mass and recurrence rate within one year were compared and analyzed. Results: the total effective rate of the observation group was 94.59%, which was significantly higher than that of the control group (75.68%). After treatment, the levels of serum C-reactive protein (CRP) and tumor necrosis factor (TNF-) in the observation group were (17.11 卤2.82 mg / L) and 2.03 卤0.46 渭 g / L), respectively, which were significantly lower than those in the control group (25.27 卤3.10 mg / L). 3.24 卤0.53 渭 g / L). After treatment, the VAS score and the maximum diameter of the mass in the observation group were (1.09 卤0.26) and 1.86 卤0.21 cm), respectively, which were significantly lower than those in the control group (2.21 卤0.30). 3.06 卤0.24 cm). (4) the recurrence rate of 24 cured patients in the observation group was 8.33% in one year, which was significantly lower than that in the control group (36.84%). Conclusion: Prunella vulgaris oral liquid can improve the therapeutic effect, reduce inflammation, relieve pain and reduce the recurrence rate.
【作者单位】：郑州人民医院;
【基金】：国家自然科学基金面上项目(81172874)
【分类号】：R655.8

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