右美托咪定复合舒芬太尼静脉镇痛对腹腔镜胃切除患者术后肠功能的影响

发布时间：2019-05-24 10:02

【摘要】：目的:观察右美托咪定复合舒芬太尼术后静脉镇痛对腹腔镜胃切除患者术后肠功能的影响。方法:择期行腹腔镜胃切除患者60例,术后使用静脉自控镇痛,随机分为两组:右美托咪定组(S组)和右美托咪定复合舒芬太尼组(SD组)。记录两组患者术后第1次肠排气时间、肠功能指数(bowel function index,BFI)、术后静息和咳嗽时疼痛数字评分(numerical rating scales,NRS)、首次使用哌替啶的时间和术后48 h内哌替啶总量、术后不良反应(呼吸抑制、恶心、呕吐)。结果:SD组患者术后第1次肠排气时间为术后(67.2±3.5)h,与S组(73.1±5.3)h相比,差异具有统计学意义(P0.05);SD组与S组术后BFI≤28.8的患者分别为26例(86.7%)和19例(63.3%)(P0.05);SD组患者术8、16、24、36、48 h静息NRS和术后4、8、16、24、36、48 h咳嗽NRS均显著低于S组(P0.05)。SD组患者术后首次使用哌替啶时间为(8.2±2.4)h,与S组(4.3±1.9)h相比,差异具有统计学意义(P0.05);SD组与S组哌替啶使用量分别为(70.5±21.9)mg和(105.4±32.2)mg,两组比较,差异具有统计学意义(P0.05);术后恶心发生率SD组和S组分别为4例(13.3%)和11例(36.7%),差异具有统计学意义(P0.05)。结论:右美托咪定复合舒芬太尼术后镇痛能有效减轻腹腔镜胃切除患者术后疼痛,减少哌替啶的用量,促进患者术后肠功能恢复。
[Abstract]:Objective: to observe the effect of intravenous analgesia with dexmetiomide combined with sufentanil on intestinal function in patients with laparoscopic gastroresection. Methods: sixty patients undergoing laparoscopic gastroresection were randomly divided into two groups: right metomipramine group (S group) and right metomide combined with sufentanil group (SD group). The first intestinal exhaust time, intestinal function index (bowel function index,BFI), postoperative rest and cough pain score (numerical rating scales,NRS), the time of first use of pethidine and the total amount of pethidine within 48 hours after operation were recorded. Postoperative adverse reactions (respiratory suppression, nausea, vomiting). Results: the first intestinal exhaust time in SD group was (67.2 卤3.5) h, which was significantly different from that in S group (73.1 卤5.3) h (P 0.05). There were 26 patients (86.7%) and 19 patients (63.3%) with BFI 鈮，

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