应用三维扫描技术测量评估透明质酸矫正鼻唇沟皱褶的术后效果
发布时间：2019-05-30 11:45
【摘要】：目的：通过三维扫描技术对以透明质酸填充矫正鼻唇沟皱褶的术后效果进行量化评估分析,建立一种全新的面部鼻唇沟测量评估方法,并对该测量方法的可行性、精确性进行验证。方法：本研究通过对40例鼻唇沟评分在3分、4分的受试者,使用透明质酸进行鼻唇沟的注射填充,对受试者术前术后的鼻唇沟严重程度和面部整体美容效果进行了评价。以VTOP三维扫描仪采集其术前及术后各时间点的三维数据,并将鼻唇沟注射前的三维数据作为参考基线,采用Geomagic Qualify 13.0软件测量比较患者鼻唇沟注射前后的三维数据,动态评估鼻唇沟注射前后的有效体积、2D尺寸、三维偏差的效果差异。结果：1.所有受试者均未出现变态过敏反应、迟发性过敏反应等严重的过敏反应,局部出现的肿胀、疼痛,无特殊处理于一周内自行好转。2.鼻唇沟严重程度及面部整体美容效果评价结果显示受试者和研究者在各时间点的评分均值趋势基本一致,注射后四个月鼻唇沟皱褶的评分均较注射前下降,面部整体美容效果的改善程度约75%,但受试者评分均值低于研究者评分低。3.以三维扫描软件测得的鼻唇沟有效体积各时间点的比较,术后一周鼻唇沟部位测量体积为0.50ml,一月测量体积为0.56ml,二月测量体积为0.49ml,三月测量体积为0.43ml,四月时测量体积为0.32ml；并对不同时间点的测量体积与实际注射量之间进行了回归分析,统计学结果显示术后一周测量值与浅层注射量存在高度线性相关(R方=0.56,p0.05),而其它时间点均不存在线性相关。4.2D尺寸分析发现术后一周鼻外侧区改善高度为2.38mm,术后一月为2.06mm,术后二月为2.Olmm,术后三月为1.48mm,至四月时为0.85mm,占术后一周的比值为35.6%,随时间延长改善高度逐渐下降。5.精确度验证中术后一周的有效体积测量值与实际注射量无差异,P0.05,没有统计学意义。其回归线性分析结果显示二者具有高度相关的线性关系,P0.05,有统计学意义。可重复性验证获得的双侧测量值的标准差分别为0.032、0.018,该测量方法可重复性好、精确度高。结论：1.经过四个月的临床研究验证三维扫描技术可以用来长期测量评估鼻唇沟皱褶填充的术后效果。2.该测量方法经过验证具有高精确度、良好的可重复性,值得进一步推广应用。3.透明质酸注射填充矫正鼻唇沟皱褶具有很好的效果,且安全可靠。
[Abstract]:Objective: to quantitatively evaluate and analyze the postoperative effect of hyaluronic acid filling in correction of nasolabial groove fold by three-dimensional scanning technique, and to establish a new method for measuring and evaluating facial nasolabial groove, and the feasibility of this method is also discussed. Verify the accuracy. Methods: 40 subjects with nasolabial sulcus score of 3 and 4 were filled with hyaluronic acid, and the severity of nasolabial sulcus before and after operation and the overall facial cosmetic effect were evaluated. The three-dimensional data before and after injection were collected by VTOP three-dimensional scanner, and the three-dimensional data before injection of nasolabial sulcus were used as reference baseline. the three-dimensional data before and after injection were measured and compared by Geomagic Qualify 13.0 software. The effective volume, 2D size and three dimensional deviation of nasolabial groove before and after injection were evaluated dynamically. Results: 1. All the subjects did not have allergic reactions, delayed allergic reactions and other serious allergic reactions, local swelling, pain, no special treatment within a week self-improvement. 2. The evaluation results of the severity of nasolabial sulcus and the overall facial cosmetic effect showed that the average score of the subjects and the researchers at each time point was basically the same, and the score of nasolabial sulcus wrinkle decreased four months after injection compared with that before injection. The improvement of the overall facial beauty effect was about 75%, but the average score of the subjects was lower than that of the researchers. 3. The effective volume of nasolabial groove measured by three-dimensional scanning software was compared at each time point. The measured volume of labial sulcus was 0.50ml one week, 0.56ml in one month, 0.49ml in February and 0.43ml in three months. The measured volume was 0.32 ml in April. The regression analysis was carried out between the measured volume and the actual injection volume at different time points. The statistical results showed that there was a high linear correlation between the measured volume and the shallow injection volume one week after operation (R square = 0.56, p0.05). There was no linear correlation at other time points. 4.2D size analysis showed that the height of the lateral nasal area was 2.38 mm, 2.06 mm, 2.Olmm 2 months, 1.48 mm 3 months and 0.85 mm 1 month, 2.06 mm, 1.48 mm and 0.85 mm respectively one week after operation, 2.06 mm 1 month, 2.Olmm 2 months after operation, 1.48 mm 3 months after operation and 0.85 mm at 4 months after operation. The ratio of 35.6% was 35.6% one week after operation, and the height decreased gradually with the prolongation of time. 5. There was no significant difference between the effective volume measurement and the actual injection volume one week after operation, but there was no significant difference between P0.05 and the actual injection volume. The results of regression linear analysis showed that there was a highly correlated linear relationship between them, P0.05, which was statistically significant. The standard deviation of bilateral measurements obtained by repeatability verification is 0.032 and 0.018, respectively. the method has good repeatability and high accuracy. Conclusion: 1. After four months of clinical study, it has been verified that three-dimensional scanning technique can be used to measure and evaluate the postoperative effect of nasal labial groove wrinkle filling for a long time. 2. The measurement method has been proved to have high accuracy and good repeatability, and it is worth further popularizing and applying. Hyaluronic acid injection filling has a good effect on correction of nasal labial groove wrinkle, and it is safe and reliable.
【学位授予单位】：东南大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R62;R765.9
本文编号：2488808
[Abstract]:Objective: to quantitatively evaluate and analyze the postoperative effect of hyaluronic acid filling in correction of nasolabial groove fold by three-dimensional scanning technique, and to establish a new method for measuring and evaluating facial nasolabial groove, and the feasibility of this method is also discussed. Verify the accuracy. Methods: 40 subjects with nasolabial sulcus score of 3 and 4 were filled with hyaluronic acid, and the severity of nasolabial sulcus before and after operation and the overall facial cosmetic effect were evaluated. The three-dimensional data before and after injection were collected by VTOP three-dimensional scanner, and the three-dimensional data before injection of nasolabial sulcus were used as reference baseline. the three-dimensional data before and after injection were measured and compared by Geomagic Qualify 13.0 software. The effective volume, 2D size and three dimensional deviation of nasolabial groove before and after injection were evaluated dynamically. Results: 1. All the subjects did not have allergic reactions, delayed allergic reactions and other serious allergic reactions, local swelling, pain, no special treatment within a week self-improvement. 2. The evaluation results of the severity of nasolabial sulcus and the overall facial cosmetic effect showed that the average score of the subjects and the researchers at each time point was basically the same, and the score of nasolabial sulcus wrinkle decreased four months after injection compared with that before injection. The improvement of the overall facial beauty effect was about 75%, but the average score of the subjects was lower than that of the researchers. 3. The effective volume of nasolabial groove measured by three-dimensional scanning software was compared at each time point. The measured volume of labial sulcus was 0.50ml one week, 0.56ml in one month, 0.49ml in February and 0.43ml in three months. The measured volume was 0.32 ml in April. The regression analysis was carried out between the measured volume and the actual injection volume at different time points. The statistical results showed that there was a high linear correlation between the measured volume and the shallow injection volume one week after operation (R square = 0.56, p0.05). There was no linear correlation at other time points. 4.2D size analysis showed that the height of the lateral nasal area was 2.38 mm, 2.06 mm, 2.Olmm 2 months, 1.48 mm 3 months and 0.85 mm 1 month, 2.06 mm, 1.48 mm and 0.85 mm respectively one week after operation, 2.06 mm 1 month, 2.Olmm 2 months after operation, 1.48 mm 3 months after operation and 0.85 mm at 4 months after operation. The ratio of 35.6% was 35.6% one week after operation, and the height decreased gradually with the prolongation of time. 5. There was no significant difference between the effective volume measurement and the actual injection volume one week after operation, but there was no significant difference between P0.05 and the actual injection volume. The results of regression linear analysis showed that there was a highly correlated linear relationship between them, P0.05, which was statistically significant. The standard deviation of bilateral measurements obtained by repeatability verification is 0.032 and 0.018, respectively. the method has good repeatability and high accuracy. Conclusion: 1. After four months of clinical study, it has been verified that three-dimensional scanning technique can be used to measure and evaluate the postoperative effect of nasal labial groove wrinkle filling for a long time. 2. The measurement method has been proved to have high accuracy and good repeatability, and it is worth further popularizing and applying. Hyaluronic acid injection filling has a good effect on correction of nasal labial groove wrinkle, and it is safe and reliable.
【学位授予单位】：东南大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R62;R765.9
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