肥胖对初次人工全髋关节置换术临床疗效影响的Meta分析
发布时间：2019-08-09 17:39
【摘要】：[目的]用Meta分析的方法探讨肥胖对初次人工全髋关节置换术(total hip arthroplasty,THA)临床疗效的影响。[方法]计算机检索数据库Pub Med、EBSCO、The Cochrane Library、Wan Fang、CNKI中关于肥胖对全髋关节置换术临床疗效的文献,检索时限为2016年8月1日之前。按纳入、排除标准进行前瞻性病例对照研究筛查,采用Newcastle Ottawa Scale(NOS)文献质量评价量表对文献进行质量评估,采用Rev Man 5.2软件进行Meta分析。[结果]纳入18篇文献,10 047例患者,肥胖组2 985例,非肥胖组7 062例。Meta分析结果显示:与非肥胖组相比,肥胖组可以显著增加THA手术时间(WMD=10.82,95%CI[4.83,16.82],P=0.000 4)、术后脱位率(RR=2.08,95%CI[1.55,2.79],P0.000 01)、感染率(RR=3.68,95%CI[2.18,6.22],P0.000 01)、失血量(WMD=169.14,95%CI[73.24,265.05],P=0.000 5),显著降低Harris Hip Score(HHS)评分(WMD=-3.40,95%CI[-5.41,-1.40],P=0.000 9);但两组住院时间(WMD=-0.19,95%CI[-0.38,-0.00],P=0.05)差异无统计学意义。[结论]肥胖增加人工全髋关节置换手术时间、失血量及术后脱位、感染并发症发生率,影响患者术后髋关节功能恢复。肥胖对初次人工全髋关节置换术临床疗效产生负面影响。
[Abstract]:Objective to investigate the effect of obesity on the clinical efficacy of primary total hip arthroplasty (total hip arthroplasty,THA) by Meta analysis. [methods] the literature on the clinical effect of obesity on total hip arthroplasty in Pub Med,EBSCO,The Cochrane Library,Wan Fang,CNKI was searched by computer for a period of time before August 1, 2016. According to the inclusion and exclusion criteria, the prospective case-control study was screened, the quality of the literature was evaluated by Newcastle Ottawa Scale (NOS) literature quality evaluation scale, and the Meta analysis was carried out by Rev Man 5.2 software. [results] 18 articles were included, including 10 047 patients, 2985 obese patients and 7 062 non obese patients. Meta analysis showed that compared with non obese group, obese group could significantly increase THA operation time (WMD=10.82,95%CI [4.83, 16.82], P 鈮，
本文编号：2524917
[Abstract]:Objective to investigate the effect of obesity on the clinical efficacy of primary total hip arthroplasty (total hip arthroplasty,THA) by Meta analysis. [methods] the literature on the clinical effect of obesity on total hip arthroplasty in Pub Med,EBSCO,The Cochrane Library,Wan Fang,CNKI was searched by computer for a period of time before August 1, 2016. According to the inclusion and exclusion criteria, the prospective case-control study was screened, the quality of the literature was evaluated by Newcastle Ottawa Scale (NOS) literature quality evaluation scale, and the Meta analysis was carried out by Rev Man 5.2 software. [results] 18 articles were included, including 10 047 patients, 2985 obese patients and 7 062 non obese patients. Meta analysis showed that compared with non obese group, obese group could significantly increase THA operation time (WMD=10.82,95%CI [4.83, 16.82], P 鈮，
本文编号：2524917
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