中国原发性开角型青光眼患病率meta分析

发布时间：2018-03-25 02:30

本文选题：原发性开角型青光眼(POAG)　切入点：患病率　出处：《中国公共卫生》2016年09期

【摘要】：目的综合定量评价中国原发性开角型青光眼(POAG)的患病率,为我国POAG的防治工作提供参考依据。方法检索中国知网数据库、万方数据服务平台、维普中文科技期刊全文数据库、Pub Med数据库、EMbase数据库和Web of Science数据库,全面收集国内外1990年1月1日—2015年7月1日公开发表的关于POAG患病的相关文献;采用Note Express 2软件对纳入的文献进行剔重,应用Comprehensive Meta Analysis Version 2.2.064软件进行meta分析。结果最终纳入20篇文献(中文文献12篇,英文文献8篇),涉及15个省市共201 111人,其中POAG患者1 254例,中国POAG总体患病率为0.8%(95%CI=0.6%~1.2%);亚组分析结果显示,男性POAG患病率为0.9%(95%CI=0.5%~1.6%),高于女性患病率的0.8%(95%CI=0.5%~1.4%),差异有统计学意义(Z=2.229,P=0.038);南方地区POAG患病率为0.9%(95%CI=0.4%~1.8%),高于北方地区POAG患病率的0.8%(95%CI=0.5%~1.2%),差异有统计学意义(Z=2.332,P=0.034);漏斗图和Egger检验结果(t=0.864,P=0.199)均未显示纳入的文献存在明显的发表偏倚。结论中国POAG患病率相对较低,POAG患病率男性高于女性、南方地区高于北方地区。
[Abstract]:Objective to evaluate quantitatively the prevalence of primary open-angle glaucoma (Poag) in China, and to provide a reference for the prevention and treatment of POAG in China. The full text database of Chinese scientific and technological journals in Weipu, Pub Med database and Web of Science database, were collected from January 1, 1990 to July 1, 2015, which were published at home and abroad on the disease of POAG. Note Express 2 software was used to sift the literature, and Comprehensive Meta Analysis Version 2.2.064 was used to analyze meta. Results 20 articles were included (12 in Chinese and 8 in English, involving 201 111 people in 15 provinces and cities). Among them, 1 254 patients with POAG, the overall prevalence of POAG in China was 0. 8%, 0. 6% CI0. 6 and 1. 2%, the results of subgroup analysis showed that, The prevalence rate of POAG in males was 0.995 CI0.5, which was higher than that in females. The difference was statistically significant. The prevalence rate of POAG in the south was 0.995 CI0.5 / 1.80.The incidence of POAG was higher than that of POAG in the northern region (0.895 CI0.5 / 1.2), and there was no significant difference between them; the funnel map and the results of Egger examination were 0.864P0 / 0.1990.There was no significant difference in the incidence rate of POAG in the northern region (P = 0.034, P = 0.034, P = 0.034, P = 0.034), and the results of the funnel map and the Egger test were 0.864Pm / 0.1990.The prevalence rate of POAG in the southern region was 0.995 / 95 / 0.5 / 1.20, which was significantly higher than that in the northern region, and the difference was significant (P < 0.05). Conclusion the prevalence of POAG in China is relatively low, and the prevalence of Poag is higher in males than in females. The south is higher than the north.
【作者单位】：泰山医学院公共卫生学院;西安交通大学基础医学院;泰安市中心医院眼科;
【分类号】：R775.2

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