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角膜绷带镜应用于治疗角膜穿孔及近穿孔的效果评价

发布时间:2018-04-03 20:23

  本文选题:角膜穿孔 切入点:角膜绷带镜 出处:《基因组学与应用生物学》2017年05期


【摘要】:评价角膜绷带镜治疗角膜穿孔及近穿孔的临床效果。收集2014年6月~2015年6月期间因角膜穿孔或近穿孔角膜在浙江大学医学院附属第二医院眼科中心接受角膜绷带镜治疗,并在配戴前后评估患者主观症状,使用裂隙灯检查,眼压,眼前节照相,角膜荧光素染色,最佳矫正视力等指标对患者眼表进行综合评价。并记录整个随访过程中戴角膜绷带镜可能引起的并发症。所有患者在停戴绷带镜后均随访3月以上。研究期间共有符合要求的病例19例(19眼),这些患者中包括暴露性角膜炎引起角膜溃疡穿孔4例,角膜穿孔伤4例,反复病毒性角膜炎导致的神经营养性角膜溃疡穿孔3例,移植物抗宿主反应病导致3例角膜穿孔,1例翼状胬肉术后角膜溃疡穿孔,3例白内障术后角膜溃疡穿孔,1例化学伤引起。19例患者治疗结果:10例近穿孔的角膜病变患者治疗后角膜溃疡面积愈合,穿孔创面修复,没有发生角膜穿孔;8例全层角膜穿孔的患者治疗后角膜创口闭合,前房深度恢复,眼表形态结构得到有效恢复;1例全层角膜穿孔角膜绷带镜配戴不稳脱落。在角膜绷带镜佩戴期间没有发现任何继发感染及其他并发症。角膜绷带镜是治疗角膜穿孔或近穿孔的有效手段,是一种安全有效的辅助治疗方法。
[Abstract]:To evaluate the clinical effect of corneal bandage in the treatment of corneal perforation and near-perforation.From June 2014 to June 2015, patients with corneal perforation or near perforation were treated with corneal bandage in the Eye Center of the second affiliated Hospital of Zhejiang University Medical College. The subjective symptoms of the patients were evaluated before and after wearing, and the intraocular pressure was examined with slit lamp.Anterior segment photography, corneal fluorescein staining and best corrected visual acuity (BCVA) were used to evaluate the ocular surface of the patients.The possible complications of corneal bandage during the follow-up were recorded.All patients were followed up for more than 3 months after bandage.During the study period, there were 19 cases of corneal ulcer perforation caused by exposure keratitis, 4 cases of corneal perforation injury and 3 cases of neurotrophic corneal ulcer perforation caused by repeated viral keratitis.Graft-versus-host response disease results in 3 cases of corneal perforation, 1 case of corneal ulcer perforation after pterygium, 3 cases of corneal ulcer perforation after cataract surgery, 1 case of chemical injury, and 1 case of chemical injury.The area of corneal ulcer healed after treatment.After treatment, the corneal wound was closed, the depth of anterior chamber was restored, and the morphology and structure of the ocular surface were recovered effectively.No secondary infections or other complications were found during the corneal bandage wear.Corneal bandage is an effective method for the treatment of corneal perforation or near-perforation, and is a safe and effective adjuvant treatment.
【作者单位】: 浙江大学医学院附属第二医院眼科中心;宁波市第一医院太学眼科中心;
【基金】:浙江大学医学院附属第二医院眼科中心对本研究的支持
【分类号】:R772.2

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