先天性特发性眼球震颤的手术治疗及眼动仪在疗效评价中的作用研究

发布时间：2018-05-19 03:04

本文选题：先天性眼球震颤 + 特发性　；参考：《昆明医科大学》2012年硕士论文

【摘要】：目的： 1、探讨先天性特发性眼球震颤(Congenital Idiopathic Nystagmus,CIN)患者手术治疗前后整体视功能的变化情况。 2、探讨眼动仪(Eye-tracker)在先天性特发性眼球震颤手术疗效评价中的作用。方法：本实验选择2011年1月至2012年3月期间在昆明医科大学第四附属医院眼科收治的伴有代偿头位的25例先天性特发性眼球震颤患者,经过详细的眼部专科检查及其他相关检查后给予所有患者手术治疗(中间带移位术)。 1、所有患者于术前及术后给予远近视力、远近立体视功能及对比敏感度检查。 2、所有患者于术前及术后采用眼动仪检查眼震参数的变化。 3、采用SPSS17.0统计学软件对所有检测数据进行统计分析。结果： 1、所有CIN患者除1例患者手术前后视力无变化外,其余患者手术后单眼、双眼的远视力及近视力均较手术前提高,组间比较差异有显著性(P0.05)。 2、除1例患者术后代偿头位尢变化外,其余患者代偿头位均有明显改善甚至完全消失。 3、所有患者术后第一眼位及术前静止眼位的震频、震幅、震强均较术前第一眼位减小,术后注视持续时间均较术前延长,各组间比较差异有显著性(P0.05)：此外,仅术前注视持续时间与术前近视力呈直线相关(P0.05),其余均无相关性(P0.05)。 4、所有患者术后远近立体视锐度及在各空间频率下对比敏感度均较术前有不同程度的提高,与术前相比差异均有统计学意义(P0.05)。结论： 1、手术治疗是先天性特发性眼球震颤最主要的治疗方法,通过手术不仅可以纠正代偿头位,提高患者的视力,同时有利于整体视功能的恢复。 2、眼动仪检查可用于术前指导制定先天性特发性眼球震颤手术方案和术后客观评价手术的疗效。
[Abstract]:Objective: 1. To investigate the changes of overall visual function in patients with congenital idiopathic nystagmus before and after operation. 2. To evaluate the effect of Eye-tracker in the treatment of congenital idiopathic nystagmus. Methods: From January 2011 to March 2012, 25 patients with congenital idiopathic nystagmus were treated in the fourth affiliated Hospital of Kunming Medical University with compensatory head position. After detailed eye examination and other related examinations, all patients were given surgical treatment (intermediate band transposition). 1. All patients were examined with visual acuity, stereopsis and contrast sensitivity before and after operation. 2. The change of nystagmus parameters was examined by eye movement instrument before and after operation. 3. All the test data were analyzed by SPSS17.0 software. Results: 1. The visual acuity of all CIN patients before and after operation was not changed except for one patient. The distant and near visual acuity of both eyes were improved after operation in all patients with CIN, and there was a significant difference between the two groups (P 0.05). 2. Except for one patient, the compensatory head position was obviously improved or disappeared completely. 3. The frequency, amplitude and intensity of shock in the first eye position after operation and the rest eye position before operation were lower than those in the first eye position before operation, and the duration of fixation after operation was longer than that before operation, and there was significant difference among the three groups (P 0.05). There was a linear correlation between preoperative fixation duration and preoperative near visual acuity (P 0.05), while no correlation was found in the rest (P 0.05). 4. The stereoscopic acuity and contrast sensitivity at different spatial frequencies were improved in all patients, and the differences were statistically significant compared with those before operation (P 0.05). Conclusion: 1. Surgical treatment is the most important treatment for congenital idiopathic nystagmus. Surgery can not only correct the compensatory head position and improve the visual acuity of the patients, but also benefit the recovery of the whole visual function. 2. The ophthalmograph can be used to guide the operation of congenital idiopathic nystagmus before operation and to evaluate the curative effect objectively after operation.
【学位授予单位】：昆明医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R779.6

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