改良整体骨炎评分在慢性鼻-鼻窦炎中的临床应用

发布时间：2018-06-05 01:04

本文选题：慢性鼻-鼻窦炎 + 骨炎　；参考：《临床耳鼻咽喉头颈外科杂志》2017年21期

【摘要】：目的:探讨改良整体骨炎评分(GOSS)在慢性鼻-鼻窦炎中的临床应用价值。方法:前瞻性研究,连续纳入药物治疗无效准备行鼻内镜手术的71例慢性鼻-鼻窦炎患者,通过OsiriX软件测量鼻窦CT,根据双侧额窦、筛窦、蝶窦、上颌窦骨炎的范围及厚度行GOSS评分及改良GOSS评分(同法,只测量双侧蝶窦及上颌窦),并于术前行视觉模拟量表(VAS)、鼻腔鼻窦结局测试-22(SNOT-22)、Lund-Kennedy(L-K)、Lund-Mackay(L-M)评分,术后1年进行疗效评判,再次行VAS、SNOT-22、L-K、L-M评分。应用SPSS 23.0软件分析改良GOSS评分的临床价值。结果:(1)改良GOSS评分与GOSS之间存在显著线性正相关(r=0.913,P0.001);(2)改良GOSS评分及GOSS评分与术前及术后L-K评分、L-M评分间存在相关性,改良GOSS评分与其相关性更高(r=0.316、0.357);与主观VAS评分、SNOT-22评分之间相关性差异无统计学意义(P0.05);(3)检验不同评分者间GOSS评分与改良GOSS评分的差异,GOSS评分组内相关系数为0.933(95%CI 0.893~0.958),改良GOSS评分组内相关系数为0.947(95%CI0.916~0.967),改良GOSS评分较GOSS评分其信度及一致性更好。结论:改良GOSS评分能够更客观准确地反映慢性鼻-鼻窦炎患者骨炎程度,简化测量,信度及一致性良好,便于临床应用。
[Abstract]:Objective: to evaluate the clinical value of modified global osteositis score (GOSS) in chronic rhinosinusitis. Methods: in a prospective study, 71 patients with chronic rhinosinusitis were enrolled in the study. The CTs were measured by OsiriX software, according to bilateral frontal sinus, ethmoid sinus, sphenoid sinus, bilateral frontal sinus, ethmoid sinus and sphenoid sinus. The range and thickness of maxillary sinus osteositis were evaluated with GOSS score and modified GOSS score (same method, bilateral sphenoid sinus and maxillary sinus were measured, visual analogue scale was performed before operation, nasal sinus outcome test -22 SNOT-22 Lund-Kenneth L-Knn Lund-MackayL-Mm), and the curative effect was evaluated one year after operation. VASN SNOT-22 and L-KN-M scores were performed again. The clinical value of modified GOSS score was analyzed by SPSS 23. 0 software. Results there was a significant linear positive correlation between the modified GOSS score and the GOSS score. There was a significant correlation between the modified GOSS score and the GOSS score and the L-K score before and after the operation. The correlation between modified GOSS score and GOSS score was higher than that of SNOT-22 score. There was no significant difference between modified GOSS score and SNOT-22 score.) the difference of GOSS score and modified GOSS score between the two groups was significant (P < 0.05). The correlation coefficient of GOSS score and modified GOSS score was 0.8930.58in the group with improved GOSS score and modified SNOT-22 score, and there was no significant difference in the correlation between the modified score and the SNOT-22 score (P < 0.05). The correlation coefficient of GOSS score group was 0.947 ~ 95% CI 0.916 ~ 0.967m. The reliability and consistency of modified GOSS score was better than that of GOSS score. Conclusion: the modified GOSS score can more objectively and accurately reflect the degree of osteitis in patients with chronic rhinosinusitis, simplify the measurement, have good reliability and consistency, and be convenient for clinical application.
【作者单位】：首都医科大学附属北京同仁医院耳鼻咽喉头颈外科耳鼻咽喉头颈外科教育部重点实验室;首都医科大学研究所附属儿童医院耳鼻咽喉科;首都医科大学大兴医院耳鼻咽喉科;
【基金】：北京市医院管理局“登峰”人才培养计划(No:DFL20150202) 北京市教育委员会科技计划重点项目(No:KZ201410025029) 院内科研种子基金(No:2016-YJJ-ZZL-017)联合资助
【分类号】：R765

【相似文献】